标签： 武汉耍耍网

On December 8th, the State Council Joint Prevention and Control Mechanism held a press conference to introduce the situation of further optimizing the implementation of epidemic prevention and control measures and answer media questions.

Graded and classified treatment

How do medical institutions do a good job in graded and classified treatment of key populations?

Guo Yanhong, director of the Medical Emergency Department of the National Health and Wellness Commission, said that in order to make overall plans for the layout and utilization of medical resources, the key point is to do a good job in the medical treatment and management of those who are seriously ill and have serious risk factors in COVID-19, and we have classified and treated those infected with COVID-19 virus.

First, for mild and asymptomatic infected people, those who have no basic diseases or whose basic diseases are in a stable period, they can take care of themselves at home.

Second, this part of patients with severe illness or serious risk should be admitted to designated hospitals. In order to ensure the treatment of this part of patients with severe illness or serious risk, we require that hospitals with strong comprehensive ability and high treatment level should be selected as designated treatment hospitals, and at the same time, they should be equipped with strong medical staff.

Thirdly, there are still some patients who have basic diseases or are mainly suffering from other diseases and go to general hospitals or specialized hospitals for treatment. In the process of treatment, they may be COVID-19-positive after testing. For these people, we have asked general hospitals and specialized hospitals to set up buffer zones, whether in outpatient, emergency or inpatient areas, so as to ensure that these patients can be treated and meet the needs of people’s medical services. Read the original > > >

What kind of symptoms do you need to see a doctor in a medical institution?

Wang Guiqiang, director of infectious diseases department of Peking University First Hospital, said that if the following five situations occur, it is recommended to contact community doctors. If the illness is serious, you can contact 120 to go to the hospital for diagnosis and treatment.

The first situation is dyspnea or shortness of breath.

The second situation is that after drug treatment, you still have a fever. If it exceeds 38.5 degrees Celsius for more than 3 days, you should go to the hospital.

The third situation is that the original underlying diseases are obviously aggravated. For example, when the medication for hypertension is uncontrollable, the medication for diabetes is uncontrollable or there are other critical risks, you must go to the hospital for treatment in time.

The fourth situation is that children have some drowsiness, refusal to eat, diarrhea, vomiting, etc., which will not be relieved after treatment, and they will have to go to the hospital for treatment for more than two days.

The fifth is that pregnant women have headaches, dizziness, palpitation, shortness of breath or abnormal fetal movement, etc., and they should also go to the hospital for further diagnosis and treatment. Read the original > > >

nucleic acid testing

From what aspects has the scope and frequency of nucleic acid detection been reduced?

He Qinghua, a first-class inspector, said that further optimization measures require further optimization of nucleic acid detection, emphasizing that nucleic acid detection should focus on areas and personnel with high risk of infection, mainly reducing the scope and frequency of nucleic acid detection from the following aspects:

First, not to carry out all-staff nucleic acid testing according to administrative regions.

Second, except for special places such as nursing homes, welfare homes, medical institutions, child care institutions, primary and secondary schools, negative proof of nucleic acid testing is not required.

Third, cross-regional migrants will no longer be examined for negative nucleic acid test certificates or health codes, and landing inspections will no longer be carried out.

Fourth, according to the needs of epidemic prevention work, antigen testing can be carried out.

In addition, it is also required to carry out nucleic acid testing for employees in high-risk positions in accordance with the relevant provisions of Article 20 optimization measures, and the scope of nucleic acid testing shall not be expanded.

Employees in high-risk positions mainly include:

Read the original > > >

What are the special places that need to provide negative nucleic acid certificates and health codes?

He Qinghua, the first-class inspector of the Department of Transmission and Prevention of the National Bureau of Disease Control and Prevention, said that although the pathogenicity of the mutant strains in Omicron is obviously weakened, the risk of serious illness is higher for the elderly and key people with basic diseases, especially those who live in nursing homes and welfare homes, as well as places where special people are concentrated, such places are prone to cluster epidemics once the source of infection is introduced, so it is necessary to provide negative proof of nucleic acid testing for foreigners entering these special places. People who enter other general places, including those who take public transport and cross-regional migrants, do not need to provide negative proof of nucleic acid test, nor do they need to carry out landing inspection, but they should do personal protection, wear masks regularly, and reduce gathering and interpersonal contact. The new 10 measures also suggest that large enterprises and some specific places can determine some prevention and control measures by themselves, and all localities can take targeted measures according to the local epidemic situation. At the same time, it is mentioned in the 20 measures that "one enterprise, one policy" and "one park, one policy" can be adopted for the prevention and control of some key enterprises, and the new 10 measures are a further continuation and update of the 20 measures.

How often do employees in high-risk positions need to carry out nucleic acid testing?

Wang Liping, a researcher at the Center for Disease Control and Prevention of China, said that according to the ninth edition of the prevention and control plan and 20 optimization measures, the employees in high-risk positions are mainly divided into two categories:

The first category is extremely risky, which refers to the entry personnel, goods, people in direct contact with the environment, staff in centralized isolation places, medical staff in designated medical institutions and fever clinics in general medical institutions,They are required to conduct closed-loop management during the operation and conduct nucleic acid testing every day;

The second category refers to some employees who are closely related to residents’ lives, such as Shangchao, Express Delivery, Takeaway, etc., who have intensive working environment, frequent contacts and strong mobility. For such people, we should also do a good job in monitoring and nucleic acid testing.Nucleic acid testing is required twice a week.

home quarantine

What factors should people consider when choosing home isolation and centralized isolation?

Wang Guiqiang, director of the Department of Infectious Diseases of the First Hospital of Peking University, said that close contacts need some basic conditions to choose home isolation: it is best to have a separate room and good ventilation; If you share the bathroom, you should do a good disinfection treatment; If the family stays at home independently, they should be able to take care of themselves in life; People at home must stay indoors and refuse all kinds of visits. In this case, we still suggest that close contact with people can be isolated at home.

We emphasize that when we are isolated at home, if there are elderly people, infants and so on who need to be taken care of at home, then we should pay attention to personal protection to avoid potential transmission risks, and we should wear masks and do a good job of hand hygiene. At the same time, antigen testing should be carried out every day, and once it is positive, it should be reported in time. At the same time, do self-monitoring after being positive. When it is negative, you should also do a good job of daily self-symptom monitoring, including whether you have fever, cough and shortness of breath. If these manifestations appear, you should also report them to the community in time.

The elderly, pregnant women, infants and people suffering from basic diseases such as cardiovascular diseases must report to the community in time for special needs, including medication and treatment, when observing at home. In case of emergency, they should also seek medical treatment in time.

How to do personal protection for isolated people at home?

Wang Guiqiang, director of the Infectious Diseases Department of the First Hospital of Peking University, said that it is necessary to do a good job of personal protection for isolated people at home, and keep as little contact with family members as possible, and keep a certain distance if they contact. Include the following points that we emphasize:

First, the living room should be ventilated every day, and good ventilation is very important to reduce the spread of respiratory infectious diseases.

Second, the bathroom, bathroom, if it is best to use it alone, it should be disinfected every day. If it is shared, it must be staggered, and it should be disinfected well after use to avoid family transmission.

Third, do a good job in hand hygiene and environmental disinfection, including paying attention to hand hygiene during cooking and dining.

Fourth, when coughing or sneezing, be sure to cover it with a paper towel and throw it into the trash can to avoid the potential risk of aerosol transmission caused by splashing.

Fifth, used paper towels, masks, disposable gloves and other household garbage are put into plastic bags and placed in special trash cans.

Another thing we should pay attention to is that personal items should not be mixed and separated from family members as much as possible, because the items themselves may also pose the risk of virus transmission.

If the medical staff are infected with Covid-19, will they be treated at home or continue to work?

Guo Yanhong, director of the Medical Emergency Department of the National Health and Wellness Commission, said that medical staff is a very special group. Due to their special positions, they will receive a large number of patients every day, so they face the highest risk of infection and the work is very heavy. It can be said that occupational exposure is inevitable.Once medical personnel are infected with Covid-19, they should also follow the relevant requirements of the "New Ten Articles".However, in order to minimize the occupational exposure risk of medical staff, we put forward a series of requirements for the management of medical institutions. Read the original > > >

Sealing and control measures

Units and buildings with "mixed pipe positive" detected no longer need to be sealed?

Wang Liping, a researcher at the Transmission and Prevention Department of China CDC, said that when the mixed tube is found to be positive, the relevant departments will inform the mixed inspection personnel as soon as possible, so that they can implement the local isolation measures, and at the same time, they will arrange personnel to take samples at home for review as soon as possible.Therefore, people in the same building and unit as those who are positive for mixed inspection do not need to be temporarily blocked.

When the recheck results are all negative, the mixed inspection personnel will immediately remove the isolation measures. However, if the door-to-door recheck results are positive, the control measures should be implemented in time, and the close contact should be controlled in time according to the results of field investigation and risk judgment, the risk area should be delineated, and the relevant epidemic situation should be handled well. Read the original > > >

Can only one positive infected person be detected without delineating high-risk areas?

Wang Liping, a researcher at the Center for Disease Control and Prevention of China,For the case that only one case is detectedIf the risk of communication in his work place, residence and activity place is relatively low, and after the secret connection is controlled in time, there is no risk of community communication after judgment, at this time, it is not necessary to delimit high-risk areas.

For a large number of households, a unit or a building may have hundreds of households.According to the current situation and risk judgment, according to the new ten articles, only the floors or households with high exposure risk can be judged to minimize the inconvenience caused by the epidemic to people’s lives.

After the high-risk area is demarcated, if no new infections are detected for five consecutive days, the seal can be released in time to avoid long-term seal control.. The new article 10 also mentioned that people with asymptomatic infection, mild illness or even close contact can choose home isolation. Therefore, it is very likely that there are some people in the community who are sealed off. For the newly infected people who are detected in the high-risk area after the risk area has been sealed off, if they live with the positive people who are strictly quarantined at home or are close to each other, there is no risk of community transmission outside the home after the judgment. In this case, even if they are positive, it will not affect the time to unseal the whole high-risk area, and they will still be unsealed without new ones for five consecutive days. Read the original > > >

Vaccination for the elderly

Why do the elderly need vaccination?

Xia Gang, Director of the Department of Health and Immunization, said that the current epidemic situation is still severe and complicated, and vaccination still has good effects in preventing severe illness and death. Vulnerable people such as the elderly can easily develop into severe illness, critical illness and even death after being infected with Covid-19, and vaccination with COVID-19 vaccine will benefit the most. There are quite a few disabled and semi-disabled elderly people in China who live at home for a long time and rarely go out. However, they may still be infected during the company or visit of relatives, which may lead to illness or even serious illness and death. Therefore, it is still necessary to vaccinate.

According to Xia Gang, according to research, compared with young people, the risk of serious illness after COVID-19 infection is 5 times, 7 times and 9 times respectively, and the risk of death is 90 times, 220 times and 570 times respectively. If the elderly over 80 years old are not vaccinated with one dose, their risk of death is about 14.7%; If one dose of vaccine is inoculated, the risk of death will be reduced to 7.16%; If three doses of vaccine are inoculated, the risk of death will be reduced to 1.5%. Compared with no vaccination, the risk of death decreased by 9.3 times after vaccination with 3 doses. Read the original > > >

What services and conveniences will be provided for the elderly when they are vaccinated?

Xia Gang introduced that in view of the mobility of these elderly people, in order to enable them to vaccinate more conveniently, we have continued some previous good practices, including using mobile vaccination vehicles, opening special vaccination sessions for the elderly and opening green channels for vaccination for the elderly. At the same time, it is also suggested that all localities can send medical personnel with rich experience in diagnosis, treatment and vaccination to form vaccination teams, carry common equipment and medicines needed during observation after vaccination, and provide home vaccination services for disabled and semi-disabled elderly people, so that these elderly people can complete vaccination without leaving home.

Editor Wang Xiaolin proofreads Zhai Yongjun.

　　China Overseas Chinese Network, March 9 (Xinhua) According to the report of WeChat official account, the Spanish version of the European Times, the Spanish Ministry of Economic Affairs has initiated the formulation of the "Creation and Development Law" and will implement digital and interconnected invoices through the platform of the Ministry of Finance. This law requires all companies, large and small enterprises, shops and even professionals to have the function of issuing electronic invoices. All computer-based billing procedures must be officially recognized. The program can send the electronic invoice to the tax bureau.

　　According to reports, the government said that this move will help to "reduce transaction costs and promote commercial transparency by digitizing commercial relations, and also described it as" a key lever that can effectively solve overdue payments in commercial operations ". However, it is also acknowledged that the primary goal of launching electronic invoices is to obtain reliable information about effective payment. The current system cannot obtain this information, but if the electronic invoice of the Ministry of Finance is used, all this information will be obtained.

　　In addition, the report said that enterprises and individuals who still do not have the function of issuing electronic invoices after two years will be fined 10,000 euros.

Three major US stock indexes overnightMixed up and down,S&P 500 indexUp 0.09% to 5308.13 points,Nasdaq composite indexIt rose by 0.65% to 16,794.88 points.Dow Jones industrial averageIt fell by 0.49% to 39,806.77 points.

Among the US stocks overnight,A total of 117 Chinese stocks rose and 151 Chinese stocks fell..

Popular Chinese stocksAmong them, Alibaba fell by 0.32%, Pinduoduo by 0.40%, Netease by 0.23%, JD.COM by 1.47%, Baidu by 1.55%, New Oriental by 1.00%, Billy by 3.54% and Iqiyi by 4.94%.

New forces of building carsAll fell, LI fell by 12.78%, Weilai fell by 1.14% and Xpeng Motors fell by 0.24%.

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　　Covid-19 is thought to originate from bats, and it is 96.2% similar to RaTG13 (collected by Shi Zhengli, Wuhan Institute of Virology, Chinese Academy of Sciences, in Yunnan, China in 2013) in nucleotide sequence level. However, it is a kind of novel coronavirus that has not been detected in humans and other animals before, and its appearance has brought many new problems to be solved urgently, including whether other pets, livestock and poultry may be infected by Covid-19 besides humans?

　　On April 8th, local time, the top academic journal Science published the paper "Susceptibility of Ferrets, Cats, Dogs, and Different Domestic Animals to SARS-coronavirus-2" online. The purpose of this study is to find out some questions: Will Covid-19 be transmitted to other animal species, thus becoming a "reservoir" of infection? Covid-19 infection has many clinical manifestations in humans, ranging from mild infection to death, so how is it manifested in other animals? With the development of vaccines and antiviral drugs, which animals can be used to simulate the effects of these drugs or vaccines on humans most accurately?

　　In order to solve these problems, research teams from the State Key Laboratory of Veterinary Biotechnology of Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences and the National High-level Biosafety Laboratory of Animal Disease Prevention and Control evaluated the susceptibility of different model experimental animals, pets and livestock to Covid-19, infected Covid-19 through experiments, observed the clinical manifestations and pathological changes of vaccinated animals and cohabiting animals, and detected the viral load of organs and tissues, the emission of respiratory and intestinal viruses, and the seroconversion of antibodies against Covid-19 in animals.

　　Their research shows that Covid-19 has weak replication ability in dogs, pigs, chickens and ducks, but it can replicate efficiently in ferrets’ upper respiratory tract and cats’ respiratory system and digestive system. Experimental infected cats can spread Covid-19 through the air; Some cats can cause serious illness or even death after infection, and the illness of young cats is obviously more serious than that of older cats.

　　Histopathological observation confirmed that virus infection in cats can cause lung inflammation and intestinal mucosal damage to varying degrees. Immunohistochemical study showed that there were a large number of virus infections in mucosal epithelium and olfactory bulb cells of upper respiratory tract (nasal cavity, maxilla, tonsil), mucous gland epithelial cells of trachea and bronchial mucosa, and intestinal mucosal epithelium.

　　The correspondent of this paper is Chen Hualan, academician of China Academy of Sciences, chief scientist of the innovation team of animal influenza basic and prevention research in Harbin Veterinary Research Institute of China Academy of Agricultural Sciences, Bu Zhigao, director of Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences and director of the national high-level biosafety laboratory for animal disease prevention and control, and Wu Guizhen, secretary of the Party Committee of Institute of Viral Disease Prevention and Control of China CDC and director of BSL-3 laboratory. Previously, on March 31st, local time, the research team had taken the lead in publishing the research on the preprint platform bioRxiv.

　　It is worth mentioning that the National High-level Biosafety Laboratory for Animal Disease Prevention and Control is one of the existing two P4 laboratories in China, and the other is in Wuhan National Biosafety Laboratory of Chinese Academy of Sciences. All the experiments of Covid-19 infection in this study were carried out in P4 laboratory, which was approved by the Ministry of Agriculture and Rural Affairs of China. Animal research and animal welfare programs were approved by the Animal Experimental Ethics Committee of China Academy of Agricultural Sciences.

　　According to the press release issued by official website, Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences, different coronaviruses have been prevalent in mammals and poultry, but most of these coronaviruses are limited to specific species of animals and generally cannot infect humans. Similarly, several common coronaviruses in humans do not infect other animals. However, some coronaviruses from bats, such as SARS and MERS virus, can often infect many animals and humans.

　　At present, Covid-19 is popular among a wide range of people in the world, and the risk of introducing animals in close contact with human beings is increasing. Therefore, it is urgent to study the susceptibility of domestic animals in close contact with human beings to Covid-19, evaluate whether domestic animals are exposed to Covid-19 hazards and become potential intermediate hosts, and provide scientific basis for prevention and control of Covid-19.

　　In addition, in view of the current global epidemic situation of COVID-19, it is very likely that it will evolve into a common infectious disease, and it is urgent to establish a stable and reliable animal infection model to meet the needs of vaccine and drug research and development evaluation.

　　The research team stressed that the monitoring of cat COVID-19 should be regarded as an auxiliary means to eliminate the current Covid-19 epidemic. They called for close monitoring and protection of cats in epidemic areas, avoiding their contact with infectious sources and preventing them from becoming possible transmission hosts or storage hosts.

　　In addition, it was previously questioned that cats infected with COVID-19 were caused by large doses under laboratory conditions. However, in addition to this research, on April 3rd, Academician Jin Meilin, professor of the State Key Laboratory of Agricultural Microbiology of Huazhong Agricultural University, director of the Key Laboratory of Veterinary Diagnostic Preparations of the Ministry of Agriculture, director of the Research Center for Emerging Infectious Diseases of Wuhan Institute of Virology, Chinese Academy of Sciences, and researcher Shi Zhengli, director of the Key Laboratory of Highly Pathogenic Biology and Biosafety of Chinese Academy of Sciences, also published a study on the preprint platform bioRxiv. Through the investigation of cat serum, they found that the serum ELISA test of 102 cats collected after the outbreak of COVID-19 in Wuhan showed that the serum from 15 cats (14.7%) was positive for Covid-19 receptor binding domain (RBD).

　　Nadia, a 4-year-old tiger from Bronx Zoo in new york, USA, was recently diagnosed with Covid-19. On April 5, local time, the US Department of Agriculture issued a statement confirming that a tiger in a zoo in new york was diagnosed with Covid-19, and several other lions and tigers also showed symptoms of respiratory diseases. Officials at the Bronx Zoo in new york said that nadia, three other tigers and three African lions had symptoms of dry cough and loss of appetite, but they are expected to recover. Public health officials believe that these animals were infected by an asymptomatic employee.

　　Covid-19 can be replicated in the upper respiratory tract of ferrets for up to 8 days, but it will not cause serious illness or death.

　　Ferrets are often used as animal models of human respiratory viruses. Therefore, the research team first tested ferrets’ sensitivity to Covid-19.

　　Two Covid-19 strains were used in this study: F13-E from Wuhan South China Seafood Market and CTan-H from a patient infected with Covid-19.

　　The research team inoculated 10 5 PFU (Plaque Forming Unit) F13-E or CTan-H into ferrets through nose respectively, and euthanized them on the 4th day after inoculation (P.I.). The turbinate, soft palate, tonsil, trachea, lung, heart, spleen, kidney, pancreas, small intestine, brain and liver of each ferret were collected, and the viral RNA was determined by qPCR and virus titration.

　　Viral RNA：A in ferrets’ organs or tissues: A, F13-E, B, CTAN-H..

　　The results showed that viral RNA and infectious virus were detected in the turbinate, soft palate and tonsil of all four ferrets, but not in other tissues.

　　C, virus titer in organs or tissues of ferrets inoculated with F13-E, D and CTAN-H.

　　The research team believes that these results show that Covid-19 can replicate in the upper respiratory tract of ferrets, but it has not been detected in other tissues.

　　In order to study the replication dynamics of virus in ferrets, the research team intranasally inoculated 6 ferrets with 10^5pfu of F13-E(3) or CTan-H(3), and then placed them in three isolated cages. On the 2nd, 4th, 6th, 8th and 10th day, ferret nasal wash and rectal swab were collected for virus RNA detection and virus titration. At the same time, their body temperature and COVID-19 signs were monitored for two weeks.

　　Viral RNA in the nasal wash of ferrets inoculated with F13-E(E) and CTan-H(F). Viral titers in the nasal wash of ferrets inoculated with F13-E(G) and CTan-H(H).

　　The results showed that viral RNA was found in the nasal wash of all six ferrets on the 2nd, 4th, 6th and 8th day. Viral RNA was also found in some rectal swabs, but the copy number was significantly lower than that of nasal wash. Infectious virus was detected in nasal wash of all ferrets, but none of them was found in rectal swab.

　　One ferret in each group developed fever and loss of appetite on the 10th and 12th days respectively. In order to investigate whether these symptoms are caused by virus replication in the lower respiratory tract, the research team euthanized the two ferrets on the 13th day and collected their organs for virus RNA detection.

　　However, except for the ferret turbinate inoculated with CTan-H, the low copy number was detected, and no viral RNA was detected in any other tissues or organs.

　　Pathological studies showed that two ferrets euthanized on the 13th day had severe lymphoplasmacytic vasculitis and vasculitis, the number of type II alveolar cells, macrophages and neutrophils in alveolar septa and alveolar cavities increased, and the lungs had mild bronchiolitis.

　　The asterisk indicates that the animals were euthanized on the 13th day after inoculation, and the other four animals were euthanized on the 20th day.

　　Covid-19 antibody was detected in all ferrets by ELISA and neutralization test, and the antibody titers of two ferrets euthanized on the 13th day were significantly lower than those euthanized on the 20th day.

　　In order to further study whether Covid-19 was replicated in ferrets’ lungs, the research team inoculated 8 ferrets with 10^5 pfu of CTan-H through trachea, and euthanized 2 animals on the 2nd, 4th, 8th and 14th days, respectively, and detected virus RNA in tissues and organs.

　　Among the two ferrets euthanized on the second day and the two ferrets euthanized on the fourth day, the researchers only detected viral RNA； in the turbinate and soft palate of one of them. Among the two ferrets euthanized on the eighth day, viral RNA； was detected in the soft palate of one ferret and in the turbinate, soft palate, tonsil and trachea of the other ferret. No viral RNA was detected in the two ferrets euthanized on the 14th day.

　　These results indicate that Covid-19 can replicate in the upper respiratory tract of ferrets for up to 8 days without causing serious illness or death.

　　At the end of the paper, the research team also mentioned that, comparatively speaking, Covid-19 is different from other influenza viruses that can replicate in the upper respiratory tract and lower respiratory tract of ferrets, and even human SARS-CoV. Covid-19 is only replicated in ferrets’ nasal bones, soft palate and tonsils. It can also replicate in the digestive tract, but even if the virus is inoculated in the trachea, the virus is still not detected in the lungs of ferrets.

　　Cats are highly susceptible to "cat-to-cat transmission": the monitoring of cat Covid-19 should be regarded as an auxiliary means of epidemic prevention and control.

　　It is worth noting that cats and dogs are in close contact with humans, so the research team thinks that besides laboratory animals like ferrets, it is very important to know the susceptibility of domestic animals that often live with humans to COVID-19 for the control of Covid-19.

　　The research team first studied the replication of Covid-19 in cats. Five 8-month-old subadult domestic cats (inbred lines) were intranasally inoculated with 10^5pfu of CTan-H, and two of them were scheduled to be euthanized on the sixth day to evaluate the virus replication in their organs. Three cats were put in separate cages in the isolator. In order to monitor the spread of respiratory droplets, an uninfected cat was placed in a cage adjacent to each cat vaccinated with the virus.

　　Because 8-month-old cats are aggressive, it is difficult to carry out routine nasal cleaning on them. In order to avoid possible harm, the research team collected the feces of these cats and checked the viral RNA in their organs after euthanasia.

　　Virus RNA was detected in the nasal bone, soft palate and tonsils of two sub-adult domestic cats euthanized on the 6th day, and virus RNA was also detected in the trachea of one cat and the small intestine of the other cat. However, no viral RNA was detected in any lung samples of these two cats.

　　Infectious viruses were detected in the nasal bones, soft palate, tonsils and trachea of these cats, but no infectious viruses were found in the small intestine with positive viral RNA.

　　The spread of Covid-19 among cats.

　　In the study of virus transmission, RNA virus was detected in the feces of two vaccinated cats on the third day, and RNA virus was detected in the feces of all three vaccinated cats on the fifth day. Among the three cats at risk of virus exposure, viral RNA was detected in the feces of one cat on the third day.

　　Virus-infected cats with positive feces were euthanized on the 11th day. Virus RNA was detected in the soft palate and tonsils of the infected cats and in the nasal bones, soft palate, tonsils and trachea of the exposed cats, indicating that respiratory droplets spread between cats.

　　On the 12th day, the research team euthanized the remaining cats. Viral RNA was detected in the tonsils of one virus-infected cat and the nasal bone, soft palate, tonsils and trachea of another virus-infected cat, but it was not detected in any organ or tissue of the two virus-exposed cats.

　　Through ELISA and neutralization test, Covid-19 antibody was detected in all three cats inoculated with virus and one cat exposed to virus.

　　Covid-19 replicates efficiently in respiratory system and digestive system of infected cats, causing pathological damage and inflammatory reaction. Histopathological and immunohistochemical study on cats that died or were euthanized three days after virus infection. (a) The arrangement of nasal mucosa epithelium is disordered, cilia fall off (arrow), and lymphocytes in lamina propria infiltrate (arrow). (b) The tonsil epithelial cells are degenerated and necrotic, and the surface of mucosal epithelium (asterisk) is covered with cell fragments and neutrophils (arrow). (c) Epithelial degeneration and necrosis of tracheal mucosa (arrow), with mucus (asterisk) mixed with a large number of cell fragments on the surface. (d) Epithelial necrosis of tracheal mucous glands and infiltration of lymphocytes (arrow). (e) Normal lung tissue structure of uninfected cats. (f) Aggregation of inflammatory cells in pulmonary blood vessels and coagulation of fibrin (arrow). (g) A large number of macrophages and lymphocytes infiltrated in alveoli, that is, alveolar septa. (h) Infiltration and proliferation of alveoli and alveolar septitis. (i) Some cells in the epithelium of small intestine are degenerated and necrotic, and lymphocytes in the lamina propria are moderately infiltrated (arrow). (j) A large number of epithelial cells of turbinate mucosa were positive for virus antigen (brown). (k) A large number of exfoliated cells in tonsil mucosa epithelium and mucosa surface were positive for virus antigen (brown). (l) A large number of virus antigens were positive (brown) in serous cells of tracheal mucous glands. (m) A large number of small intestinal mucosal epithelial cells were positive for virus antigen (brown). Ruler line A, I = 100 μ m, B-H, J-L = 200 μ m, M = 500 μ m

　　The research team also repeated the above-mentioned replication and transmission research in sub-adult cats in young cats (70-100 days). Histopathological studies on the samples of young cats who died or were euthanized on the third day after being inoculated with the virus showed that the nasal cavity and tracheal mucosa epithelium and lungs of the two cats had a lot of damage.

　　These results indicate that Covid-19 can be effectively replicated in cats, and young cats are more susceptible to infection. More importantly, the virus can spread from cat to cat through respiratory droplets.

　　Next, the research team also studied the replication and spread of Covid-19 in dogs, and the results showed that dogs were less sensitive to Covid-19. Similar studies also show that pigs, chickens and ducks are not sensitive to Covid-19.

　　Overall, the research team found that ferrets and cats are highly sensitive to Covid-19, dogs are less sensitive, and domestic animals including pigs, chickens and ducks are not sensitive to the virus.

　　In addition, it is reported that Covid-19 uses angiotensin-converting enzyme 2 (ACE2) as its receptor to enter cells, and ACE2 is mainly expressed in type II lung cells and serous epithelial cells of ferrets’ tracheal-bronchial submucosal glands. Therefore, the research team believes that the potential mechanism to prevent Covid-19 from replicating in ferrets’ lower respiratory tract remains to be studied.

　　The results of this study show that ferrets can be used as animal models for vaccine and drug evaluation in Covid-19. Dogs, pigs, chickens and ducks are not susceptible to Covid-19, which has important guiding significance for the traceability of virus hosts; More importantly, cats are highly susceptible to Covid-19.

　　The research team called for close monitoring and protection of cats in epidemic areas to avoid contact with infectious sources and prevent them from becoming possible transmission hosts or storage hosts. The monitoring of cat COVID-19 should be regarded as an auxiliary means to eliminate the current Covid-19 epidemic.

　　Paper link: https://science.sciencemag.org/content/sci/early/2020/04/07/science.abb7015.full.pdf.

    Xinhua News Agency, Beijing, March 6th　Question: How do you view China’s price movement? -The second question and answer of China economy in the two sessions.

    Xinhua News Agency reporter Wei Yukun and Wu Yu

    Since last year, China’s price increase has been running at a low level, which has aroused some people’s worries about China’s deflation. How to treat China’s price movement situation? Is China’s economy really in deflation?

    During the two sessions of the National People’s Congress, the reporter interviewed many NPC deputies, Chinese People’s Political Consultative Conference members and authoritative experts to analyze this issue and respond to external concerns.

   Does low prices mean deflation?

    Since October last year, the consumer price index (CPI) has been declining year-on-year, and it will drop by 0.8% in January 2024. At the same time, the national producer price index (PPI) continued to decline.

    The low price has caused some worries about whether China’s economy will fall into deflation.

    To judge whether we are caught in deflation, we must first clarify the concept. Generally speaking, in economics, deflation mainly refers to the continuous negative growth of prices and the downward trend of money supply, which is usually accompanied by economic recession. This depends not only on the "shape" of price operation, but also on the "state" of money supply and the "potential" of economic development.

    -Price operation: generally low, maintaining a moderate upward trend.

    According to the government work report submitted for deliberation on the 5th, the consumer price of China residents rose by 0.2% in 2023. This data is in stark contrast to the high inflation in major developed economies.

    Jin Li, member of Chinese People’s Political Consultative Conference and vice president of south university of science and technology of china, said that last year, the core CPI excluding volatile food and energy prices rose by 0.7% year-on-year, indicating that the supply and demand of industrial consumer goods and service consumption in China were generally stable. The year-on-year decline of PPI also decreased by 5.4% from the highest in June last year to 2.5% in January 2024.

    Since last year, China’s monthly price level has always fluctuated moderately within a reasonable range. In January 2024, CPI rose by 0.3% month-on-month, which has been rising for two consecutive months.

    -Money supply: the total amount is moderate and the rhythm is stable.

    By the end of January 2024, the balance of broad money (M2) in China was 297.63 trillion yuan, up 8.7% year-on-year. Under the background of high base in the same period last year, it maintained a reasonable growth rate.

    The scale of social financing is a comprehensive indicator of financial support for the real economy. In January, the scale of social financing in China increased by 6.5 trillion yuan, 506.1 billion yuan more than the same period of last year.

    -economic development: the overall recovery is improving.

    In 2023, China’s economy generally rebounded, with a GDP growth rate of 5.2%, which was faster than the average growth rate of 4.5% in the three years of the epidemic, and also significantly faster than the economic growth rates of 2.5% in the United States, 0.5% in the euro zone and 1.9% in Japan, making it an important engine of global economic growth.

    Since 2024, China’s manufacturing purchasing managers index, SME development index and other indicators have rebounded from last December. The International Monetary Fund (IMF) recently raised its forecast for China’s economic growth this year and cast a "vote of confidence" for China’s economy.

    "Deflation is often the result of long-term accumulation of structural problems in economic operation. Judging deflation should not only focus on one or two price indicators." Huang Maoxing, deputy to the National People’s Congress and vice president of Fujian Academy of Social Sciences, said that on the whole, there is no deflation in China, let alone deflation spillover, and the so-called "economic deflation in China" is totally a false proposition.

    Not long ago, ING reported that the discussion about deflation in China was exaggerated by the outside world. In January, the overall CPI and core CPI in China both rose month-on-month, reflecting that China has not fallen into a "deflation spiral".

    "We don’t expect an overall deflationary trend in China." Gita Gopinath, First Vice President of IMF, said not long ago.

   What are the reasons for the low price increase?

    Prices are related to economic operation and affect people’s lives. At present, the low price increase in China is the result of multiple factors.

    "After the smooth transition of epidemic prevention and control, domestic production has accelerated recovery, logistics has remained smooth, and product supply is sufficient. However, demand is constrained by factors such as expected instability and income distribution differentiation, and recovery will take some time." Xu Guangjian, vice president of China Price Association, said that the time difference between supply and demand recovery is the main factor for the lower prices.

    Commissioner Jin Li said that in 2022, due to the Ukrainian crisis, food and energy prices were higher, which made the CPI increase in 2023 relatively low. In addition, the price of pork occupies a high weight in China CPI. Due to the abundant supply of live pigs and pork and the sluggish consumption of superimposed pork, the domestic pig price continues to fall, which lowers the CPI increase.

    Input factors also have an impact on China’s prices. After the epidemic, in order to cope with high inflation, major central banks in the United States and Europe quickly and intensively adjusted their monetary policies, and the year-on-year increase of CPI in the United States and Europe has dropped from the previous high of about 10% to the current 3%. "The inflation level in developed economies has fallen faster than expected, which has an impact on the price level in China." Pan Gongsheng, governor of the People’s Bank of China, said.

    Xing Ziqiang, chief economist of Morgan Stanley in China, said that China’s lower prices may have a positive spillover effect on global trade goods prices, which will help alleviate the "sequela" of unconventional stimulus policies adopted by some economies in response to high inflation.

    The experts interviewed agreed that the factors that caused the current low price operation in China are mainly phased, cyclical and seasonal, not trending, and its influence should not be exaggerated.

    This year’s government work report sets the expected target of annual consumer price increase at around 3%. According to the plan report submitted for review on the 5th, the main consideration for setting this goal is to comprehensively analyze the hikes of price changes in 2023 and the new price increase factors in 2024. It is expected that consumer prices will rise moderately in 2024.

    "This expected goal is consistent with last year’s expected goal, in line with the overall trend of domestic price stabilization and recovery, and leaves some room for strengthening macro-policy regulation and deepening price reform." Yu Miaojie, deputy to the National People’s Congress and president of Liaoning University, said.

   How to prevent the risk of deflation?

    Delegates and experts interviewed said that although the low domestic price operation is temporary, we should be alert to and guard against deflation risks, and actively and effectively solve problems such as insufficient effective domestic demand and overcapacity in some industries.

    -Strengthening macro-policy control.

    The government work report pointed out that the liquidity should be kept reasonable and sufficient, and the scale of social financing and money supply should match the expected goals of economic growth and price level.

    "Maintaining a reasonable and sufficient liquidity is an effective measure to prevent deflation risks. This year’s government work has clearly promoted the steady decline of comprehensive social financing costs, which is expected to further stimulate the effective demand of the real economy and enhance residents’ willingness to consume and invest. " Ceng Gang, director of Shanghai Finance and Development Laboratory, said.

    A proactive fiscal policy should moderately increase efforts, improve quality and increase efficiency; A prudent monetary policy should be flexible, moderate, accurate and effective; Incorporate non-economic policies into the consistency assessment of macro-policy orientation … A number of arrangements in this year’s government work report have strengthened policy co-ordination to ensure that efforts are made in the same direction and joint efforts are formed.

    -Promote the formation of a virtuous circle in which consumption and investment promote each other.

    Han Baojiang, a member of Chinese People’s Political Consultative Conference and a professor at the Central Party School (National School of Administration), said that at present, the key to preventing deflation risks is to expand domestic demand, release the potential vitality of the super-large-scale market, and enhance the ability and confidence to resist external imported risks.

    When deploying this year’s tasks, the government work report pointed out that the implementation of the strategy of expanding domestic demand should be organically combined with deepening the structural reform on the supply side, so as to better coordinate consumption and investment and enhance the pulling effect on economic growth.

    Optimize the consumption environment, carry out the "consumption promotion year" activity and implement the "rest assured consumption action"; Deepen the cultivation and construction of international consumption center cities; Promote the construction of additional national debt projects with high quality; We will implement a new cooperation mechanism between the government and social capital, and encourage private capital to participate in major project construction … The government work report and the plan report will focus on expanding domestic demand this year.

    "With the implementation of a series of policies to expand domestic demand, giving full play to the key role of investment in optimizing the supply structure and promoting the upgrading of domestic consumption structure, the domestic economic cycle will be further smooth." Qu Yongyi, member of Chinese People’s Political Consultative Conference and secretary of the Party Committee of the Institute of Industrial Economics of the Chinese Academy of Social Sciences, said.

    Ayhan Gauss, deputy chief economist and director of the forecasting bureau of the World Bank, said that a series of policies adopted by China at present are very correct, which can boost consumer confidence and consumption in the short term, and enhance the long-term economic growth potential through firm reforms.

This week, OPPO announced the latest technological progress in AI, performance, communication and privacy security, including the first handset/hands-free dual-mode satellite call for smart phones, the first 7 billion-parameter large model for end-side applications, the tidal architecture that debuted and many other cutting-edge technologies.

The brand-new technology portfolio announced this time will fully implement the next-generation flagship product Find X7 series, set a brand-new technical benchmark for the flagship mobile phone in 2024, and bring consumers an innovative flagship experience that refreshes standards.

Release handset/hands-free dual-mode satellite call, leading the evolution of satellite interphone to satellite mobile phone.

OPPO released the satellite antenna pattern control technology, which will realize the innovative experience of handset/hands-free dual-mode satellite call for the next generation flagship. This technology can dynamically adjust the radiation pattern of satellite antenna, make the antenna beam aim at the satellite dynamically, and ensure that users can keep connected and talk with the satellite in both handset and hands-free conversation postures.

Lu Bao, a terminal antenna expert in OPPO hardware engineering, said: "We are very happy to realize the latest breakthrough in satellite antenna technology in the next generation flagship product for the first time through continuous research and accumulation and using a series of innovative technologies and patents. Through satellite communication technology and fully upgraded antenna, smart communication and near-field communication technology, we expect users to get a reliable communication experience in the whole scene. "

The traditional satellite communication mobile phone adopts single antenna design, and it can’t meet the demand of transmitting power in the head-to-hand state. It can only support the use of hands-free mode, which will lead to problems such as unclear communication in harsh weather environment such as strong wind.

OPPO’s brand-new handset/handsfree dual-mode satellite call makes the mobile phone satellite call experience evolve from "satellite intercom mode" to "satellite phone mode" which accords with users’ intuition for the first time, helping users to obtain more efficient communication efficiency in extreme environments.

The industry’s first end-to-end application of the 7 billion parameter big model, the big model mobile phone entered the fast lane.

Facing the rapid development of large-scale model technology, OPPO officially launched the large-scale model of self-training in ODC — — After AndesGPT, it was also announced that the industry’s first 7 billion-parameter model of end-side application will be realized on Find X7 series.

Through the model compression such as high-precision 4-4bit quantization, the acceleration of reasoning engine and the hardware acceleration mode of deep cooperation with chip platform,For the first time, it brings a complete 7 billion-parameter large model to the mobile phone terminal, completely changing the way of using the mobile phone terminal AI.

Zhang Jun, general manager of OPPO Software Innovation Center, said: "OPPO’s self-trained and personalized big model — — AndesGPT contains many versions of parameters from one billion to one hundred billion, with abundant knowledge, infinite memory and good use of tools. The technical architecture of end-cloud collaboration can support diversified application scenarios.

With the cooperation of various technologies, we will also apply a large language model with 7 billion parameters and a generative visual model to the Find X7 series for the first time, which will bring a local AI experience with faster response, stronger processing ability and higher generation quality while ensuring the privacy and safety of users. "

Thanks to the complete ANDES GPT 7 billion-parameter large language model applied by end-side, Find X7 series will bring the next generation AI experience such as natural language understanding, text content summary and call voice summary.

Compared with other models on the same platform, oppoandesgpt 7 billion parameter large language model can bring 20 times faster response in the generation of 200-word prefix, and 2.5 times faster for the generation of 2000-word prefix.

At the same time, OPPO’s AndesGPT can achieve the maximum number of abstract words of 14,000, which is 3.5 times that of other models on the same platform. In terms of generation quality, compared with the 1 billion parameter model, the ANDES GPT 7 billion parameter large language model has a higher "IQ" understanding ability, which brings a more complete and accurate record to the call summarization ability.

OPPO also announced the AndesGPT generative visual model based on self-training, which will bring image semantic understanding, subject recognition and segmentation, image extension and generation capabilities to Find X7 series, and bring a new functional experience of subject elimination and real-life redrawing. AndesGPT’s generative visual mode brings a wider range of image experience to mobile phones.

Compared with other cloud models on the same platform, AndesGPT can only support human body recognition. ANDES GPT not only supports the recognition and segmentation of more than 120 kinds of subjects, but also can realize hair-level segmentation and multi-agent separation of up to six, as well as the filling and natural generation of super-large-area images, which greatly expands the application scope and practicability of the generative visual model.

In addition, the end-to-end application of AndesGPT generative visual model also brings 60% shorter generation time and higher generation accuracy compared with other models on the same platform, bringing users a more readily available generative visual experience.

Original tidal architecture, breaking through the bottleneck of chip energy efficiency

Facing the more stringent demand of flagship end users for chip energy efficiency, OPPO first announced the exclusive tidal architecture technology. As a technology stack of chip hardware and software integration, Tide Architecture has built a set of chip-level performance solutions from scene recognition, computing power demand, cache matching and computing power scheduling, which solves the problems of memory and computing separation and chip scheduling faced by mobile platforms and realizes the maximum energy efficiency performance of flagship chips.

Hong Hansheng, director of software technology planning and architecture design of OPPO, said: "Tidal architecture is a collection of chip soft and hard fusion technologies developed by OPPO, and it is a chip optimization technology created by a group of people who know chips.

In the past, from the first-level cache to the system cache has always been the technical area of chip design companies. Through the tidal architecture OPPO, it broke through the technical boundary and mastered the use of the third-level cache to the system cache. With the chip-level capabilities in no man’s land and deep water, it brought a great leap in computing efficiency to the flagship products. "

Through in-depth joint research and development with chip manufacturers, OPPO has penetrated the tidal architecture into the on-chip cache system that traditional mobile phone manufacturers can’t use finely, and jointly designed cache partition, dynamic ratio of CPU/GPU and fast channel scheme of clean data with chip manufacturers.

Through the tidal architecture, OPPO realizes the dynamic matching of system-level cache for the first time.Dynamically allocate system-level cache resources for CPU and GPU in real time according to computational tasks and rendering tasks. Through this unique technology, the tidal architecture can achieve an average energy efficiency gain of 8%.

In addition, the tidal architecture also supports a brand-new scene-level computing power and power consumption analysis model on the chip, which can realize the dynamic computing power and power consumption evaluation and analysis based on a single scene, and dynamically disassemble each computing task to the computing power distribution of each computing unit on the chip in real time, find out the best energy efficiency combination, and achieve more competitive energy efficiency performance for diverse user applications.

By accurately and dynamically scheduling the computing power of GPU, Tide Architecture can also control the display delay excellently, and realize an unprecedented continuous and smooth experience for Android flagship. In the test of simulating users to start applications 320 times a day, the standard deviation of Find X7 equipped with tidal architecture is only 11ms, which has achieved a more lasting and stable smooth performance than the same platform and other platforms.

Hong Hansheng also revealed that OPPO has begun to deeply participate in the design of the next generation of Tianqi chips and explore more possibilities of tidal architecture.

Super signal engineering, solving network problems in the whole scene

During the communication meeting, OPPO also announced a set of self-developed communication technology solutions — — Super signal engineering, through antenna technology, intelligent communication and near-field communication, enhances the full-scene communication experience of Find X7 series from outdoor to urban and from urban to indoor.

OPPO brings the highest performance four-antenna architecture to the next generation flagship product through antenna miniaturization technology and spatial distribution optimization of low-frequency four-antennas. By combining low ECC and high isolation technology, OPPO can further improve the throughput of ultra-low frequency four antennas and reduce network delay.

Facing the influence of the grip on the signal strength, OPPO specially designed the low-frequency antenna, built the signal model of OPPO’s self-developed handheld state, improved the signal condition of the mobile phone in the handheld state, and realized the signal strength enhancement of up to 7dB and an average of 3dB.

OPPO’s unique intelligent communication technology utilizes the intelligent computing service provided by Andean intelligent cloud, the industry-leading intelligent fusion link technology and the cross-layer data acceleration capability to realize the acceleration strategy of the combination of Wi-Fi and cellular multi-networks.

In addition, based on communication QoS link technology, OPPO accelerates conference data and improves conference delay through the establishment of 5G boutique private networks of three major operators.

Smart communication technology also brings AI network prediction technology to Find X7 series. By integrating AI technology, communication technology and sensing technology, Find X7 series can predict signals for different spatial forms, intelligently recommend the most appropriate internet use strategy, and provide better performance in scenarios such as short video jam of subway and optimal network probability of switching from home to home.

Through intelligent communication technology, Find X7 series will also support excellent cross-end unified communication. Through Pantanal trust chain technology, Find X7 can realize fast and non-inductive connection between mobile phone and tablet, and based on the self-developed virtual data transmission channel, the tablet has mobile phone network communication capability, and users can make calls, send and receive short messages and access the Internet with data.

Super Signal Engineering will also bring a brand-new near-field communication experience to Find X7. Using the through-the-wall mode of near-field communication, Find X7 dynamically selects the optimal transmission and reception time slots through active noise identification, and improves the anti-interference ability. Combined with radio frequency enhancement technology, Find X7 improves the uplink and downlink rates.

Through the high throughput mode, Find X7 series can use the brand-new bandwidth of 160Mhz for mobile phone moving transmission, and can complete the handling of 180GB content in less than 15 minutes.

Using the dual-antenna packet loss prevention technology, Find X7 series can also bring lower Wi-Fi network delay. Using Wi-Fi& Bluetooth full acceleration 3.0 technology, Find X7 series can solve the data transmission impact of Wi-Fi and Bluetooth in traditional solutions. Compared with other products, this technology helps Find X7 series to reduce the game delay of nearly 150ms and 18 live broadcasts.

Protect security and privacy from software to hardware.

While promoting innovation in AI, performance and communication technology, OPPO always attaches great importance to users’ privacy security, and is committed to building a comprehensive privacy protection system for users through full-link application, data management and control, and innovative functions combining software and hardware.

In order to further enhance users’ privacy protection, OPPO has brought a security solution based on the second-level security chip with the highest security level in the mobile phone industry, which will provide the terminal with the highest chip-level privacy protection.

Compared with the traditional software security scheme, the chip-level encryption method can separate the management and authorization switch of sensitive rights from the operating system and lock it into the hardware layer of the security chip, which is managed by the chip-level security subsystem.

Based on the chip-level privacy security scheme, OPPO has implemented an innovative VIP mode in the folding flagship FindN3. With OPPO’s unique three-stage physical switch, it can quickly and intuitively turn off sensitive permissions such as microphone, camera and positioning, and encrypt user privacy information at hardware level.

　　China Securities Network News (Wang Luo) started from the printing industry. Lingyun Guang has been deeply involved in the industrial machine vision industry for 20 years, and has expanded its applications to consumer electronics, new displays, new energy and other fields. Head enterprises in industries such as Apple, Huawei, Xiaomi, Foxconn, BOE and () are all important customers of Lingyun Guang.

　　On June 15th, Ling Yunguang (stock code: 688400) officially launched the inquiry offering, and will soon land in science and technology innovation board. The science and technology innovation board listing, Lingyun Guang plans to raise 1.5 billion yuan, and the fundraising direction is centered on the company’s vision planning. From industrial manufacturing to industrial intelligent manufacturing, machine vision is promising. The company will increase investment in technology research and development, continuously improve its platform-based capabilities, empower intelligent manufacturing, and help more industries achieve automation and intelligent development. The company’s development vision is to implant "eyes" and "brains" into machines and become a global leader in the fields of visual artificial intelligence and photoelectric information.

　　From agency to self-research, mastering the underlying core technology

　　According to the prospectus, Ling Yunguang was established in 2002, and started from the banknote printing industry, and carried out independent research and development through projects such as online detection of RMB gravure printing and large sheet detection; On the other hand, the agency business of foreign high-end visual devices is carried out. Since 2006, the company has successively entered the fields of printing and packaging, new display and consumer electronics, and further improved its independent research and development capabilities. At present, it has the research and development capabilities of advanced imaging, intelligent algorithms, intelligent software and automatic precision control, and independently developed core devices such as industrial cameras and light sources, which are applied to many industries.

　　The domestic machine vision started in the late 1990s. When Ling Yunguang entered this field 20 years ago, the domestic development and application were basically blank. The company started from scratch and gradually embarked on the road of independent research and development in the field of machine vision.

　　Ling Yunguang attached great importance to self-research of core technologies at the early stage of business development. During the period from 2002 to 2006, the company initially built a 100-person team with independent research and development capabilities of optical, mechanical, electrical, computing and software technologies, and started the research and development of independent software algorithms of VisionWARE. The technical accumulation in this period has created an insurmountable moat for the company’s competitors in a short period of time. Now the machine VisionWARE algorithm platform independently developed by the company has been iterated to version 5.0. Ling Yunguang is the first machine vision manufacturer in China to launch a purely independent bottom-level core algorithm library. The investment cycle of the bottom-level algorithm is quite long. It takes a lot of time and experience to optimize the core algorithm from the bottom, which makes it ahead of competitors in the same industry for about three to five years.

　　In addition, Ling Yunguang’s AI algorithm development based on deep learning, machine learning and knowledge map has also been at the forefront of the industry, forming an independent F.Brain intelligent algorithm platform, supporting factory-side and edge intelligence through edge computing, and supporting factory cloud intelligence through big data cloud computing technology. From the application point of view, the machine vision +AI technology is deeply combined to support industrial scenes.

　　It is understood that the algorithm library of the machine vision industry consists of open source vision algorithm libraries such as OpenCV, and third-party commercial payment algorithm libraries such as Vision Pro (cognex, USA), Halcon (German MVTec) and VisionWare (Ling Yunguang). Due to the long development cycle and large investment of algorithm library, companies in the industry usually develop their own application algorithms based on open source algorithm library, or independently develop and integrate with third parties, and few companies develop the underlying algorithms completely independently.

　　In addition to algorithms, Lingyun Guang has always been at the forefront of optical imaging technology, and has independently developed a series of visual core devices such as smart cameras and high-brightness special light sources. It has more than 70 patents in the optical field, and many solutions are the first to benchmark international and domestic machine vision friends, creating a brighter industrial "eye" competitiveness. At the same time, by investing in domestic CMOS sensor design company Changguang Chenxin and industrial lens professional company Hunan Changdao Optoelectronics, we will optimize the allocation of core resources and lay out the localization and autonomy of core technologies.

　　Form platform capability from system to equipment

　　After all, the banknote printing industry belongs to a special industry. After 2006, Ling Yunguang gradually expanded its business to printing and packaging, display screens, consumer electronics and other industries, and further integrated its research and development capabilities into platform-based capabilities of products and technologies, thus effectively supporting the company to achieve cross-industry development. In addition, the company began to expand its automation capability in 2016, and it took three years to gradually build automatic control technologies such as automatic assembly line and multi-axis precision manipulator.

　　Up to now, Lingyun Guang has four technical platforms, including advanced imaging, intelligent algorithm, intelligent software and intelligent automation, and comprehensive overall scheme design capability. It has 418 domestic patents and 208 software copyrights, which supports the company’s rapid expansion of downstream industries from printing to other fields, such as consumer electronics and new energy, and is also a technical base to support the company’s continuous leap-forward development in the future.

　　According to Ling Yunguang’s prospectus, up to now, the company has developed diversified intelligent visual equipment and innovative process solutions based on independent research and development of visual algorithms and AI algorithms for new display, consumer electronics, printing and packaging, new energy and other fields. Specific to the display field, the new display intelligent vision equipment products provided by Ling Yunguang can realize automatic and semi-automatic optical detection of small screen defects in TFT-LCD/OLED, covering the Cell process section and module process section, and support lighting detection when the screen is powered on and appearance detection when it is not powered on. The detection efficiency of the LCD lighting quality detector provided by it is more than 3 times that of manual work, which solves the problem of 2% low contrast stain defect detection, approaches the limit of human eyes, realizes high dynamic range detection, and has been popularized and applied in hundreds of sets in the industry.

　　Entering Apple’s industrial chain is a key milestone for Ling Yunguang, and it is also the inevitable result of technical capacity building. Five years ago, the company broke the situation that the high-end market of consumer electronic vision inspection was monopolized by foreign manufacturers such as cognex and Kearns for a long time, and became the Preferred Supplier in the field of machine vision certified by Apple, and began to provide configurable vision systems in batches.

　　"Hand", "Eye" and "Brain" cooperate to empower intelligent industrial production.

　　If configurable vision system products, such as machine vision algorithm platform developed by Ling Yunguang, can equip industrial machines with eyes and brains, then intelligent vision equipment is to implant muscles and limbs controlled by brains into the machines, thus realizing the precise control and execution of detection and production technology, and finally forming an intelligent production robot with the cooperation of hands, eyes and brains.

　　As the largest manufacturing country in the world, the penetration rate of domestic machine vision application is low, and there is still much room for growth, especially the aging population and the increase in labor costs, which also bring great demand to the machine vision industry.

　　From the demand of downstream customers, the epidemic situation in COVID-19 is complicated in recent years. Instead of reducing the budget for technology investment, downstream manufacturers have been further forced by the epidemic to strengthen their investment in industrial automation, digitalization and intelligence, and the cost reduction effect is very remarkable. In the future, the demand of downstream manufacturers for automation and intelligence is rigid and inevitable.

　　China market has become one of the fastest growing markets in the global machine vision market. According to the statistics of China Machine Vision Industry Alliance, the sales of machine vision industry in China increased from 10.18 billion yuan in 2018 to 14.42 billion yuan in 2020, with a compound growth rate of 19.02%. Thanks to the promotion of manufacturing automation and other factors, it is estimated that the sales of machine vision industry in China will increase at a compound growth rate of 27.15% from 2020 to 2023, and the sales will reach 29.6 billion yuan by 2023.

　　Under such opportunities, Lingyun Guang will continue to promote technological innovation in advanced optical imaging, software and algorithms, automation and other fields, and actively explore new application fields of industrial machine vision. At present, Ling Yunguang’s machine vision +AI products and services have achieved a high market share in consumer electronics, display panels, printing and packaging applications. According to the statistics of China Machine Vision Industry Alliance, in 2020, among the enterprises participating in the statistics (enterprises within the alliance), Lingyun Guang ranked first in the sales of machine vision industry in China.

　　According to the disclosure in the prospectus, the company is expanding its business to the field of new energy battery diaphragm detection, and has cooperated with customers such as Contemporary Amperex Technology Co., Limited. Focusing on the field of industrial manufacturing for 20 years, Lingyun Guang is expected to become the leader of industrial artificial intelligence, truly helping factories to improve quality, increase efficiency, reduce costs and reduce storage.

In today’s digital era, electronic invoices have become a common form of bills in economic activities. It is very important for individuals and enterprises to master the relevant knowledge of electronic invoices.

To master the relevant knowledge of electronic invoices, you can first obtain information through official channels. The official website of the tax department is an important source of information, which will contain detailed contents such as policy interpretation, issuance process, reimbursement regulations and so on. In addition, you can also pay attention to the official WeChat official account of the tax department and get the latest policy trends and operational guidelines in time. At the same time, corporate financial personnel can also participate in training courses organized by tax authorities to systematically learn the relevant knowledge of electronic invoices.

For individuals, when they come into contact with electronic invoices in their daily lives, they can consult the merchants about relevant issues, and know how to issue electronic invoices and how to obtain them. You can also search related knowledge articles and videos through the Internet to learn more about the use of electronic invoices and matters needing attention.

Electronic invoice has its unique format and characteristics. From the format, the common electronic invoice formats are PDF, OFD and so on. PDF format is a common one, it has good compatibility, and most devices and software can be opened for viewing. OFD format is a format of layout document independently developed by China, which has the advantages of high security and strong traceability.

The characteristics of electronic invoices are very remarkable. First, it is convenient to issue. Compared with traditional paper invoices, electronic invoices can be generated quickly through the system without filling in a lot of information manually, which greatly improves the billing efficiency. Second, it is convenient to store. Electronic invoices exist in the form of electronic data, which can be stored in computers, mobile phones and other devices without fear of loss or damage. Third, environmental protection and energy saving. Electronic invoice reduces the use of paper and conforms to the concept of green development. Fourth, the inspection is easy. Consumers and enterprises can quickly and accurately check the authenticity of electronic invoices through the official inspection platform of the tax department.

The following is a comparison table between electronic invoices and traditional paper invoices:

In a word, knowing how to acquire knowledge, format and characteristics of electronic invoices will help us to use electronic invoices more efficiently and conveniently in economic activities and adapt to the development trend of digital economy.

　　Russian video screenshot today

　　Overseas Network September 22ndAccording to the news of "Russia Today" on the 21st, some pictures and videos have been circulated on Russian social media platforms recently: a street in Barakovo is full of dead birds. This rare scene triggered a series of brain hole conjectures by netizens.

　　According to reports, this incident occurred in Barakovo, Saratov State, southwestern Russia, which is famous for its large nuclear power plant. According to videos and pictures uploaded by Russian social media users, local residents witnessed the bodies of dozens of dead birds scattered on a road.

　　Source: Russia today

　　Below the video, Russian netizens gave many conjectures about why dead birds fell from the sky. Some people blame it on natural phenomena, such as a strong wind or an accidental collision between two birds. Others think that fireworks and exhaust gas from factories may cause a large number of deaths, and some even say that it is related to 5G equipment, although this technology has not yet entered Russia.

　　"At the beginning of the nuclear disaster TV series Chernobyl, all the birds died." A comment with the highest praise linked the incident to the American HBO hit drama. The animal medical department of Saratov State is currently investigating this incident, which some people think may be related to bird flu. (Overseas Network Zhang Qi)

　　Photo: @ vision china Health Youyue Studio produced.

　　Fatty liver is becoming more and more common, and medical research suggests that it is closely related to diet. So, is there any way to "eat back" the "fat" liver that has been eaten?

　　"Yes!" Chen Zexiong, a famous Chinese medicine practitioner in Guangdong Province, pointed out that proper diet can really help the liver "slim down", which is also the treatment to eliminate the cause of fatty liver. However, people with "fat" liver should eat according to syndrome differentiation, and even cooking oil is particular. Experts also give three prescriptions: porridge, soup and tea to help patients with fatty liver to eat diet every day.

　　Medical Guidance/Provincial Famous Chinese Medicine Doctor, Chen Zexiong, Chief Physician of Chinese Medicine Department of the First Affiliated Hospital of Sun Yat-sen University, and Sun Baoguo, Deputy Chief Physician of Chinese Medicine Department of the First Affiliated Hospital of Sun Yat-sen University.

　　Text/Guangzhou Daily All-Media Reporter He Xuehua Correspondent Peng Fuxiang

　　Fatty liver is mostly physical examination, and it is found that 30% to 40% is due to obesity.

　　Two days ago, an old acquaintance and classmate came to Sun Baoguo’s clinic. She was blessed and anxious. It turned out that the old classmate was found to have fatty liver in the physical examination of the unit. "I heard that it might be cirrhosis and liver cancer, which scared me to worry about what to eat and drink!" The old classmate said.

　　There are quite a few such cases. Most patients with fatty liver only find problems during physical examination.

　　This is because most of mild fatty liver has no obvious symptoms, or only a sense of fatigue, which is easy to be ignored. However, if it develops into moderate to severe fatty liver, there will be loss of appetite, fatigue, nausea, vomiting, weight loss, right hypochondriac or right upper abdominal pain. Moreover, if the treatment of simple fatty liver is neglected, it can develop into steatohepatitis and cirrhosis for a long time.

　　Fatty liver, as its name implies, is the excessive accumulation of fat in the liver. Medicine believes that it can be caused by many causes and diseases, mainly related to obesity, diabetes, alcoholism and so on. According to relevant literature reports, simple obesity accounts for 30%~40% of the causes of fatty liver, and many patients with fatty liver have high-fat and high-cholesterol diets, which suggests that the formation of fatty liver is closely related to diet, and diet may be the direct cause of disease in the general population.　　

　　Dietotherapy can eliminate the cause of fatty liver

　　Finding and eliminating the cause is the fundamental method to treat fatty liver, such as adjusting diet structure, losing weight, abstaining from alcohol and treating the primary disease.

　　Professor Chen Zexiong pointed out that a reasonable diet is of great significance to the prevention and treatment of fatty liver, especially for patients with simple fatty liver, most of them can be recovered through reasonable diet and exercise. Therefore, if you have fatty liver, don’t be afraid and worried. It is better to actively try diet therapy and "eat back" the problems you have eaten.

　　Then how to treat fatty liver?

　　Traditional Chinese medicine believes that this disease is caused by improper drinking and eating, invasion of human body by dampness, emotional disorder, or chronic illness and physical weakness, which leads to poor qi movement, and the combination of dampness, phlegm and blood stasis, which is blocked in the blood vessels and meridians of the liver. Therefore, regulating qi-flowing, eliminating phlegm-dampness, promoting blood circulation and removing blood stasis, and clearing the liver and gallbladder are the main methods for treating this disease in traditional Chinese medicine. The choice of daily diet for patients with fatty liver should also follow this principle. While paying attention to the color, smell and taste of food, try to choose foods that meet the actual needs of individuals.

　　List of foods to help the liver "lose weight"

　　Foods with fatty liver preventing and treating effects and nutrition metabolism improving effects;

　　Patients with fatty liver who are uncomfortable with the right hypochondriac rib (that is, the right chest from the armpit to the sternum) and easy to get angry can eat more vegetables, chrysanthemum, tomatoes, shepherd’s purse, etc., which can clear away heat and cool the liver;

　　Patients with bad breath, constipation and fatty liver who overeat greasy food can eat more vegetables and fruits rich in vitamins and cellulose, such as radish, bamboo shoots, wax gourd, loofah, celery, cucumber, water chestnut and hawthorn fruit, which can clear away heat, promote bowel movement and facilitate urination;

　　Fatty liver patients with physical weakness can choose low-fat and high-protein foods such as pork lean meat, pigeon meat, rabbit meat, beef lean meat, skim milk, soybean milk, etc., which can tonify liver and kidney, replenish qi and nourish blood.

　　Food unsuitable for patients with fatty liver:

　　Pig fat, goose, duck eggs, animal oil, animal viscera and animal brain have high fat content; Crab, crab roe, squid, cuttlefish, clam meat and anchovies are high in cholesterol, so it is advisable to eat less or not. Because sugar will turn into fat in the body, which will aggravate fatty liver, it is better to eat less high-sugar foods such as litchi, longan pulp, candied fruit, preserved fruit and sugar.

　　Selection of staple food and oil:

　　It is suggested that fatty liver patients should choose vegetable oils such as vegetable oil, sesame oil, cottonseed oil and peanut oil, because they contain more unsaturated fatty acids and have the effect of lowering blood cholesterol. The staple food can be low-sugar foods such as corn flour, buckwheat flour, oat flour, bean flour and other products. These foods are coarse grains, which can reduce qi and broaden the intestines and cleanse the greasy stomach.

　　One porridge, one soup and one tea are most suitable for liver "fat"

　　Patients with fatty liver in daily life can also choose medicated diet for conditioning:

　　Hawthorn Carassius auratus soup: Take 30g of raw hawthorn, one crucian carp, 10g of immature bitter orange, appropriate amount of ginger and water, and drink the soup after cooking. Regular administration of this decoction can promote blood circulation and qi circulation, and has a certain effect on hypochondriac swelling pain or acupuncture-like pain, or hepatomegaly and purple tongue.

　　Pueraria flower tea: 15g of Pueraria flower, 10g of Salvia miltiorrhiza, 4-5 tablets of Ilex kudingcha, appropriate amount of water, boiling and simmering for 30min, and taking the juice as tea. Used for long-term alcoholism and mutual stagnation of dampness and blood stasis.

　　Codonopsis pilosula millet porridge: 10 grams of Codonopsis pilosula, 10 grams of Poria cocos, 20 grams of lentils, boiled for 30 minutes with appropriate amount of water, added with 100 grams of millet, and cooked with slow fire. For people with weak temper, such as listlessness, pale complexion and loss of appetite, this porridge can be taken frequently.

　　Special reminder that dietotherapy doesn’t work, hurry up with medication.

　　Experts pointed out that while adjusting the diet structure, patients with fatty liver should also take appropriate exercise to keep their mood comfortable, which is helpful for the treatment of fatty liver.

　　Special reminder, for those who have the primary disease or the above methods can not be effective, they must go to a regular hospital to find a specialist to deal with it, and cooperate with drug treatment to avoid delaying the illness.