Buick GL8 hybrid electric and plug-in hybrid models have been declared, and 6-seat and 7-seat versions are available.

On April 16th, the Ministry of Industry and Information Technology announced the new product announcement of the 382nd batch of "Road Motor Vehicle Manufacturers and Products Announcement" last night, and the Buick GL8 hybrid electric and plug-in hybrid models appeared.

Right part of six-seat oil-mixed car body

Six-seat oil-mixed car body rear part

Right part of seven-seat oil-mixed car body

Seven-seat oil-mixed car body rear part

The oil-mixed model is equipped with LSZ 2.0T engine; The ternary lithium battery produced by Jiangsu Zhengli Xinneng does not support external charging.

Six-seat plug-in hybrid car body right part

Six-seat plug-in hybrid rear body

Right part of seven-seat plug-in hybrid car body

Seven-seat plug-in hybrid rear body

The plug-in version is equipped with LAX 1.5T engine; Ferrous lithium phosphate produced by Jiangsu Zhengli Xinneng is used to support external charging.

Optional configuration

▲ Optional configuration

According to the application information, the length, width and height of this new car are 5219/1878/1807 mm, which are basically consistent with the fuel version. The wheelbase is 3088 mm and the maximum speed is 180 km/h. Different skylight, front bumper, rear bumper, taillight and rearview mirror styles can be installed.

Buick GL8 luzun PHEV

IT House reported yesterday that the Buick GL8 Luzun PHEV plug-in hybrid model has now been booked.

American college students suspected of dissatisfaction with scores, shot their teachers and killed themselves.

  [Global Times Comprehensive Report] Famous American public universities — — A shooting incident occurred at the University of California, Los Angeles (UCLA) on the 1st, killing two men, including the gunman who shot himself after killing. Preliminary investigation shows that the two deceased were teachers and students. Perhaps the gunman was dissatisfied with the scores of related disciplines and started to kill. US President Barack Obama has listened to the briefing on the shooting incident, which has once again triggered the debate on the issue of robbery control in American society.

  The Los Angeles Times reported on the 2nd that UCLA6 ushered in the exam and graduation season in June. At about 10 am on the 1st, the tense and orderly learning atmosphere on campus was suddenly disrupted by the continuous sound of mobile phones. All the students at school received such a short message: someone shot on campus. In just a few minutes, thousands of school students quickly sought shelter to protect themselves. People in the classroom will lock the door, then pile the tables and chairs together and block the entrance. Because the situation was still unclear at that time, some people received false information that there were "as many as four gunmen", so the school was once in panic and chaos.

  After receiving the alarm, 200 law enforcement and firefighters, including special police team and FBI agents, immediately entered the school and blocked the entrance. Helicopters circled over the incident site. Armed police searched the UCLA engineering experimental building floor by floor. Finally, they found two male bodies in an office on the fourth floor of the building. Charlie Baker, the head of the local police station, said at a later press conference that it was not difficult to infer from the wound that the gunman killed the victim first and then shot himself. The police also found a note at the scene of the murder, which is now inferred to be the suicide note left by the murderer. As the case is still in progress, the police said it was inconvenient to disclose the contents of the note. Witnesses at the scene said that the gunman wore a black dress and carried an automatic rifle into the campus that day, and fired at least three shots at the crime scene.

  CNN)2 reported on the 2nd that the alert state of UCLA campus was lifted around 12 noon that day, as the murderer was killed and the weapon was seized. The person in charge of the police said that the gun case did not involve other suspects. The school cancelled all classes on the afternoon of the 1st and said it would resume classes on the 2nd. The engineering laboratory building where the murder happened will not resume normal operation until next Monday. Teachers and students in the school said in an interview with the media that the shooting incident made them feel worried. "I can’t believe this happened in my school."

  The school confirmed that the man killed by the gunman was William Kruger, an associate professor of engineering at the school, who was only 39 years old. Kruger holds a doctorate from California Institute of Technology, focusing on mechanical engineering and aerospace engineering. According to people familiar with him, William was not only brilliant, but also kind and popular. A colleague commented: "In the highly competitive academic world, it is really rare for a person with talent and good personality like him."

  According to the report in UCLA’s journal Daily Bear, the gun case is still under investigation, and the police refused to disclose all the information about the gunman, including his identity and motive. However, a person familiar with the matter said on social media that the gunman was a student of William, and he was "extremely depressed" because of his poor grades in some courses, and he was very dissatisfied with William’s grades, which may be the motive for his murder. However, this statement has not been officially confirmed.

  The White House said that President Obama expressed great concern about the gun case. During his trip to Indiana, he listened to the briefing and asked the staff to report the latest progress to him. Eric Gasetti, Mayor of Los Angeles, expressed his condolences to the victims of the shooting and praised the teachers and students of the school for their calm and appropriate response to the crisis.

  School shootings are common in the United States. Since 2015 alone, there have been more than 20 large and small school gun cases in the United States. In the past two years, the most serious school shooting incident occurred in Roseburg, Oregon: a community college in the city was attacked by gunmen last October, killing 10 people and injuring 9 others.

  The gun case at UCLA has once again triggered a heated debate on the issue of robbery control. A few days ago, Dana Lesch, a well-known American gun advocate and popular radio anchor, made provocative remarks on Twitter, saying that UCLA’s gun case showed that gun control was meaningless in the United States. She said that California itself has extremely strict gun control measures, and UCLA campus explicitly prohibits carrying guns. In this case, the gunman was able to bring high-powered weapons in openly, and the effectiveness of the relevant measures cannot but be questioned.

According to the media, nearly 20% of college students spend more than 10,000 yuan on dinner trips.

  Data Map: It is the graduation season for college students, and college graduates from Qingdao, Shandong Province are shooting personalized graduation photo on campus.

  Reference News Network reported on June 11 that foreign media said that China is about to usher in the "graduation season" for students to graduate collectively. Graduates all want to keep good memories on campus in their own way. The "graduation economy" such as graduation dinners, travel and photo shoots has emerged from time to time and is very hot. Nearly 20% of graduates spend more than 10,000 yuan on graduation.

  According to the China media report on the website of Lianhe Zaobao on June 8th, the hotels around the school will have a "harvest season" in the graduation season of college students every year, and most students choose the hotels around the school for graduation dinner. In order to attract graduates, some hotels also advertise that "every graduate can book a table with 8.8 discount, and drinks are free".

  The owner of a restaurant near Northeast Petroleum University said that with the graduation season approaching, the peak of booking graduation dinner is coming. A coffee shop near Heilongjiang Bayi Agricultural University has held a graduation party with the theme of "First Love" since May 14th.

  A graduate of Qingdao University said that since mid-May, he has had graduation dinners every night and spent a lot of money.

  He said: "Usually, the living expenses for one month are around 1000 yuan. Now I have calculated in the graduation season, and 3,000 yuan may not be enough."

  According to the report, in addition to graduation dinners, travel and photo shooting are also an indispensable part of graduates’ good memories in college.

  Since the end of last month, all kinds of innovative graduation photos have been screened on various social platforms. In addition to the traditional graduation bachelor’s clothes, graduates can rent all kinds of clothes, and many people even seek the help of photography studios to shoot creative graduation photo.

  A private photographer in Guangxi said that at present, the appointment for taking graduation photos has been arranged until the end of June, and people are still coming to consult, and the original fee has also increased from 100 yuan to 500 yuan.

  Although Xiao Qin, a graduate of the School of Finance and Economics of Guangxi University, spent a month’s living expenses shooting graduation photos, she thought it was worth it. After all, "Youth never comes again. If you can, why not record your youth?"

  According to a survey conducted by Qingdao Daily on 40 graduates from China Ocean University, China Shiyou University (East China) and Qingdao University, nearly 20% of the graduates will spend more than 10,000 yuan in graduation season, and most of them will be spent on graduation trips.

  In addition, in order to impress the interviewer in the job interview, some students spend money to buy interview clothes. Xiao Chen, a graduate of China Ocean University, spent 2,000 yuan on brand suits and leather shoes, and spent a lot of time in making resumes, specifically looking for someone to design resume templates; He spent two or three hundred yuan on printing and copying his resume alone.

  According to the report, Yuan Jinqiu, from the Department of Political Economy, School of Politics, Guangxi University, analyzed that the emergence of the "graduation economy" conforms to the laws of the market, and many businesses are ingenious in meeting the needs of graduates, which is a very positive economic situation.

  However, since graduates are not yet financially independent, most of their expenses come from their parents. In this regard, Yuan Jinqiu believes that it is ok for graduates to participate in some job hunting and graduation commemoration activities if conditions permit, but it should be appropriate.

  Wu Lianhai, consultant of the Mental Health Education and Counseling Center of China Ocean University, agrees with the above view. He said that college students’ consumption in graduation season is a way to express their classmates’ friendship, and some expenses are understandable, but the concept of face and conformity will inevitably contribute to the "graduation economy", so the expenditure in this respect must be measured.

The details of the death of American seals were revealed: they were fiercely besieged by more than 100 IS elements

  [Global Network Military Report on May 7] According to a report on the website of the US Army Times on May 4, the US Navy "Seals" commandos who died in Iraq on the 3 rd were members of a rapid reaction force. Their task was to pick up a US military operational advisory group that was attacked by "Islamic State" militants in the Kurdish region of Iraq. At 7: 50 in the morning, after receiving the report of "the troops were attacked", the US military commander ordered the rapid reaction unit where the special forces staff sergeant Charlie Keating was located to join the battle and assist those US military advisers to evacuate. When Keating and his troops arrived in the village, they found that Kurdish armed forces and American military advisers were engaged in fierce melee with the enemy.

  A national defense official said on the 3rd that at 7: 30 in the morning, about 125 "Islamic State" militants suddenly attacked the town of Taylor Askov.The militants acted in groups, with 20 armored vehicles and several car bombs, trapping more than 10 US military operational advisers. These consultants were on a one-day mission in the local area at that time, meeting with Kurdish a freedom fighter militants who had several operational outposts near the area controlled by the Islamic State.

  "There were bullets everywhere," said Colonel steve warren, a spokesman for the US Department of Defense in Baghdad. He (Keating) was hit in this gun battle. " Warren said that Keating was shot at 9: 30 am that day, and was taken by helicopter to the US military medical center in nearby Abiel for treatment at 10: 19 am, but died shortly after.

  Warren said that it is very rare to use the rapid reaction force in Iraq. The battle on the 3rd was the first time in several months that an American army called for emergency operations support. Keating, 31, is the third American soldier killed in Iraq since the US-led Coalition forces began to fight against the "Islamic State". At present, the US military is sending more ground troops to combat the "Islamic State" in Iraq and Syria.

  The US military operational advisory group entered the town of Taylor Askov at dawn. The town is less than 5 miles (1 mile is about 1.6 kilometers) from the area controlled by the "Islamic State". Warren said that the U.S. military commander had ordered the rapid reaction force to assemble and stand by in advance in case the U.S. military "advice and assistance" team was in danger.

  The "Islamic State" militants and their convoy of 20 vehicles entered the area without the knowledge of US military consultants and Kurdish armed intelligence personnel. Warren said, "You can’t monitor every inch of land all the time."

  Warren said: "The enemy was able to gather enough troops in a very secret way, including several car bombs and some bulldozers, and of course their infantry. They were able to cross the local Kurdish armed defense line, cross the front line and advance rapidly to the town of Taylor Askov. There is their goal. "

  The photos of the battle posted by the "Islamic State" on social media show that its militants drove several American Hummer military vehicles equipped with simple armor and a modified pickup truck equipped with heavy anti-aircraft machine guns. Warren said that there is no evidence that the "Islamic State" militants knew that there were Americans in the town when they launched the attack.

  Warren said that shortly after the fighting started, American planes arrived over the town of Taylor Askov, including drones, F-15s and F-16s, several B-52s and A-10s. These planes dropped dozens of bombs, destroying all 20 armored vehicles of the "Islamic State" militants, as well as two cars, a bulldozer and three mortars. According to Warren’s estimation, 58 "Islamic State" militants were killed in the air raid.

Summarize the latest questions and answers about nucleic acid detection, home isolation, etc., and the joint prevention and control mechanism in the State Council.

On December 8th, the State Council Joint Prevention and Control Mechanism held a press conference to introduce the situation of further optimizing the implementation of epidemic prevention and control measures and answer media questions.

Graded and classified treatment

How do medical institutions do a good job in graded and classified treatment of key populations?

Guo Yanhong, director of the Medical Emergency Department of the National Health and Wellness Commission, said that in order to make overall plans for the layout and utilization of medical resources, the key point is to do a good job in the medical treatment and management of those who are seriously ill and have serious risk factors in COVID-19, and we have classified and treated those infected with COVID-19 virus.

First, for mild and asymptomatic infected people, those who have no basic diseases or whose basic diseases are in a stable period, they can take care of themselves at home.

Second, this part of patients with severe illness or serious risk should be admitted to designated hospitals. In order to ensure the treatment of this part of patients with severe illness or serious risk, we require that hospitals with strong comprehensive ability and high treatment level should be selected as designated treatment hospitals, and at the same time, they should be equipped with strong medical staff.

Thirdly, there are still some patients who have basic diseases or are mainly suffering from other diseases and go to general hospitals or specialized hospitals for treatment. In the process of treatment, they may be COVID-19-positive after testing. For these people, we have asked general hospitals and specialized hospitals to set up buffer zones, whether in outpatient, emergency or inpatient areas, so as to ensure that these patients can be treated and meet the needs of people’s medical services. Read the original > > >

What kind of symptoms do you need to see a doctor in a medical institution?

Wang Guiqiang, director of infectious diseases department of Peking University First Hospital, said that if the following five situations occur, it is recommended to contact community doctors. If the illness is serious, you can contact 120 to go to the hospital for diagnosis and treatment.

The first situation is dyspnea or shortness of breath.

The second situation is that after drug treatment, you still have a fever. If it exceeds 38.5 degrees Celsius for more than 3 days, you should go to the hospital.

The third situation is that the original underlying diseases are obviously aggravated. For example, when the medication for hypertension is uncontrollable, the medication for diabetes is uncontrollable or there are other critical risks, you must go to the hospital for treatment in time.

The fourth situation is that children have some drowsiness, refusal to eat, diarrhea, vomiting, etc., which will not be relieved after treatment, and they will have to go to the hospital for treatment for more than two days.

The fifth is that pregnant women have headaches, dizziness, palpitation, shortness of breath or abnormal fetal movement, etc., and they should also go to the hospital for further diagnosis and treatment. Read the original > > >

nucleic acid testing

From what aspects has the scope and frequency of nucleic acid detection been reduced?

He Qinghua, a first-class inspector, said that further optimization measures require further optimization of nucleic acid detection, emphasizing that nucleic acid detection should focus on areas and personnel with high risk of infection, mainly reducing the scope and frequency of nucleic acid detection from the following aspects:

First, not to carry out all-staff nucleic acid testing according to administrative regions.

Second, except for special places such as nursing homes, welfare homes, medical institutions, child care institutions, primary and secondary schools, negative proof of nucleic acid testing is not required.

Third, cross-regional migrants will no longer be examined for negative nucleic acid test certificates or health codes, and landing inspections will no longer be carried out.

Fourth, according to the needs of epidemic prevention work, antigen testing can be carried out.

In addition, it is also required to carry out nucleic acid testing for employees in high-risk positions in accordance with the relevant provisions of Article 20 optimization measures, and the scope of nucleic acid testing shall not be expanded.

Employees in high-risk positions mainly include:

Read the original > > >

What are the special places that need to provide negative nucleic acid certificates and health codes?

He Qinghua, the first-class inspector of the Department of Transmission and Prevention of the National Bureau of Disease Control and Prevention, said that although the pathogenicity of the mutant strains in Omicron is obviously weakened, the risk of serious illness is higher for the elderly and key people with basic diseases, especially those who live in nursing homes and welfare homes, as well as places where special people are concentrated, such places are prone to cluster epidemics once the source of infection is introduced, so it is necessary to provide negative proof of nucleic acid testing for foreigners entering these special places. People who enter other general places, including those who take public transport and cross-regional migrants, do not need to provide negative proof of nucleic acid test, nor do they need to carry out landing inspection, but they should do personal protection, wear masks regularly, and reduce gathering and interpersonal contact. The new 10 measures also suggest that large enterprises and some specific places can determine some prevention and control measures by themselves, and all localities can take targeted measures according to the local epidemic situation. At the same time, it is mentioned in the 20 measures that "one enterprise, one policy" and "one park, one policy" can be adopted for the prevention and control of some key enterprises, and the new 10 measures are a further continuation and update of the 20 measures.

How often do employees in high-risk positions need to carry out nucleic acid testing?

Wang Liping, a researcher at the Center for Disease Control and Prevention of China, said that according to the ninth edition of the prevention and control plan and 20 optimization measures, the employees in high-risk positions are mainly divided into two categories:

The first category is extremely risky, which refers to the entry personnel, goods, people in direct contact with the environment, staff in centralized isolation places, medical staff in designated medical institutions and fever clinics in general medical institutions,They are required to conduct closed-loop management during the operation and conduct nucleic acid testing every day;

The second category refers to some employees who are closely related to residents’ lives, such as Shangchao, Express Delivery, Takeaway, etc., who have intensive working environment, frequent contacts and strong mobility. For such people, we should also do a good job in monitoring and nucleic acid testing.Nucleic acid testing is required twice a week.

home quarantine

What factors should people consider when choosing home isolation and centralized isolation?

Wang Guiqiang, director of the Department of Infectious Diseases of the First Hospital of Peking University, said that close contacts need some basic conditions to choose home isolation: it is best to have a separate room and good ventilation; If you share the bathroom, you should do a good disinfection treatment; If the family stays at home independently, they should be able to take care of themselves in life; People at home must stay indoors and refuse all kinds of visits. In this case, we still suggest that close contact with people can be isolated at home.

We emphasize that when we are isolated at home, if there are elderly people, infants and so on who need to be taken care of at home, then we should pay attention to personal protection to avoid potential transmission risks, and we should wear masks and do a good job of hand hygiene. At the same time, antigen testing should be carried out every day, and once it is positive, it should be reported in time. At the same time, do self-monitoring after being positive. When it is negative, you should also do a good job of daily self-symptom monitoring, including whether you have fever, cough and shortness of breath. If these manifestations appear, you should also report them to the community in time.

The elderly, pregnant women, infants and people suffering from basic diseases such as cardiovascular diseases must report to the community in time for special needs, including medication and treatment, when observing at home. In case of emergency, they should also seek medical treatment in time.

How to do personal protection for isolated people at home?

Wang Guiqiang, director of the Infectious Diseases Department of the First Hospital of Peking University, said that it is necessary to do a good job of personal protection for isolated people at home, and keep as little contact with family members as possible, and keep a certain distance if they contact. Include the following points that we emphasize:

First, the living room should be ventilated every day, and good ventilation is very important to reduce the spread of respiratory infectious diseases.

Second, the bathroom, bathroom, if it is best to use it alone, it should be disinfected every day. If it is shared, it must be staggered, and it should be disinfected well after use to avoid family transmission.

Third, do a good job in hand hygiene and environmental disinfection, including paying attention to hand hygiene during cooking and dining.

Fourth, when coughing or sneezing, be sure to cover it with a paper towel and throw it into the trash can to avoid the potential risk of aerosol transmission caused by splashing.

Fifth, used paper towels, masks, disposable gloves and other household garbage are put into plastic bags and placed in special trash cans.

Another thing we should pay attention to is that personal items should not be mixed and separated from family members as much as possible, because the items themselves may also pose the risk of virus transmission.

If the medical staff are infected with Covid-19, will they be treated at home or continue to work?

Guo Yanhong, director of the Medical Emergency Department of the National Health and Wellness Commission, said that medical staff is a very special group. Due to their special positions, they will receive a large number of patients every day, so they face the highest risk of infection and the work is very heavy. It can be said that occupational exposure is inevitable.Once medical personnel are infected with Covid-19, they should also follow the relevant requirements of the "New Ten Articles".However, in order to minimize the occupational exposure risk of medical staff, we put forward a series of requirements for the management of medical institutions. Read the original > > >

Sealing and control measures

Units and buildings with "mixed pipe positive" detected no longer need to be sealed?

Wang Liping, a researcher at the Transmission and Prevention Department of China CDC, said that when the mixed tube is found to be positive, the relevant departments will inform the mixed inspection personnel as soon as possible, so that they can implement the local isolation measures, and at the same time, they will arrange personnel to take samples at home for review as soon as possible.Therefore, people in the same building and unit as those who are positive for mixed inspection do not need to be temporarily blocked.

When the recheck results are all negative, the mixed inspection personnel will immediately remove the isolation measures. However, if the door-to-door recheck results are positive, the control measures should be implemented in time, and the close contact should be controlled in time according to the results of field investigation and risk judgment, the risk area should be delineated, and the relevant epidemic situation should be handled well. Read the original > > >

Can only one positive infected person be detected without delineating high-risk areas?

Wang Liping, a researcher at the Center for Disease Control and Prevention of China,For the case that only one case is detectedIf the risk of communication in his work place, residence and activity place is relatively low, and after the secret connection is controlled in time, there is no risk of community communication after judgment, at this time, it is not necessary to delimit high-risk areas.

For a large number of households, a unit or a building may have hundreds of households.According to the current situation and risk judgment, according to the new ten articles, only the floors or households with high exposure risk can be judged to minimize the inconvenience caused by the epidemic to people’s lives.

After the high-risk area is demarcated, if no new infections are detected for five consecutive days, the seal can be released in time to avoid long-term seal control.. The new article 10 also mentioned that people with asymptomatic infection, mild illness or even close contact can choose home isolation. Therefore, it is very likely that there are some people in the community who are sealed off. For the newly infected people who are detected in the high-risk area after the risk area has been sealed off, if they live with the positive people who are strictly quarantined at home or are close to each other, there is no risk of community transmission outside the home after the judgment. In this case, even if they are positive, it will not affect the time to unseal the whole high-risk area, and they will still be unsealed without new ones for five consecutive days. Read the original > > >

Vaccination for the elderly

Why do the elderly need vaccination?

Xia Gang, Director of the Department of Health and Immunization, said that the current epidemic situation is still severe and complicated, and vaccination still has good effects in preventing severe illness and death. Vulnerable people such as the elderly can easily develop into severe illness, critical illness and even death after being infected with Covid-19, and vaccination with COVID-19 vaccine will benefit the most. There are quite a few disabled and semi-disabled elderly people in China who live at home for a long time and rarely go out. However, they may still be infected during the company or visit of relatives, which may lead to illness or even serious illness and death. Therefore, it is still necessary to vaccinate.

According to Xia Gang, according to research, compared with young people, the risk of serious illness after COVID-19 infection is 5 times, 7 times and 9 times respectively, and the risk of death is 90 times, 220 times and 570 times respectively. If the elderly over 80 years old are not vaccinated with one dose, their risk of death is about 14.7%; If one dose of vaccine is inoculated, the risk of death will be reduced to 7.16%; If three doses of vaccine are inoculated, the risk of death will be reduced to 1.5%. Compared with no vaccination, the risk of death decreased by 9.3 times after vaccination with 3 doses. Read the original > > >

What services and conveniences will be provided for the elderly when they are vaccinated?

Xia Gang introduced that in view of the mobility of these elderly people, in order to enable them to vaccinate more conveniently, we have continued some previous good practices, including using mobile vaccination vehicles, opening special vaccination sessions for the elderly and opening green channels for vaccination for the elderly. At the same time, it is also suggested that all localities can send medical personnel with rich experience in diagnosis, treatment and vaccination to form vaccination teams, carry common equipment and medicines needed during observation after vaccination, and provide home vaccination services for disabled and semi-disabled elderly people, so that these elderly people can complete vaccination without leaving home.

Editor Wang Xiaolin proofreads Zhai Yongjun.

Spain will require all enterprises and shops to have the function of issuing electronic invoices, and offenders will be fined.

  China Overseas Chinese Network, March 9 (Xinhua) According to the report of WeChat official account, the Spanish version of the European Times, the Spanish Ministry of Economic Affairs has initiated the formulation of the "Creation and Development Law" and will implement digital and interconnected invoices through the platform of the Ministry of Finance. This law requires all companies, large and small enterprises, shops and even professionals to have the function of issuing electronic invoices. All computer-based billing procedures must be officially recognized. The program can send the electronic invoice to the tax bureau.

  According to reports, the government said that this move will help to "reduce transaction costs and promote commercial transparency by digitizing commercial relations, and also described it as" a key lever that can effectively solve overdue payments in commercial operations ". However, it is also acknowledged that the primary goal of launching electronic invoices is to obtain reliable information about effective payment. The current system cannot obtain this information, but if the electronic invoice of the Ministry of Finance is used, all this information will be obtained.

  In addition, the report said that enterprises and individuals who still do not have the function of issuing electronic invoices after two years will be fined 10,000 euros.

Scan of China Stock Market: A total of 151 US stocks fell overnight. Tmall 618: The first hour reached 100 million yuan. The club is now a dark horse.

Three major US stock indexes overnightMixed up and down,S&P 500 indexUp 0.09% to 5308.13 points,Nasdaq composite indexIt rose by 0.65% to 16,794.88 points.Dow Jones industrial averageIt fell by 0.49% to 39,806.77 points.

Among the US stocks overnight,A total of 117 Chinese stocks rose and 151 Chinese stocks fell..

Popular Chinese stocksAmong them, Alibaba fell by 0.32%, Pinduoduo by 0.40%, Netease by 0.23%, JD.COM by 1.47%, Baidu by 1.55%, New Oriental by 1.00%, Billy by 3.54% and Iqiyi by 4.94%.

New forces of building carsAll fell, LI fell by 12.78%, Weilai fell by 1.14% and Xpeng Motors fell by 0.24%.

[Related News]

Tmall 618: The first hour reaches 100 million yuan, and the club is now a dark horse.

According to the Economic Observer Network, at 8 pm on May 20th, Tmall 618 was put on sale. Taobao’s live broadcast started with a strong momentum, and the anchors such as Li Jiaqi, Lieer Baby, Bee Surprise Club, Lentinus edodes, KiKi of Jie Chen and Jiumei took the lead in trading over 100 million yuan. Among them, the wine sister is a new anchor dark horse.

In the first hour of the sale of Tmall 618, the turnover of Apple exceeded 1.5 billion, and the turnover of Huawei, Xiaomi and vivo exceeded 100 million.

According to CBN, Tmall 618, the first one to cancel the pre-sale, was officially launched at 8: 00 pm on May 20, and it was sold for one hour. The turnover of Apple exceeded 1.5 billion, and the turnover of brands such as Huawei, Xiaomi and vivo also quickly exceeded 100 million.

LI Li Xiang: At present, the continuous growth of L series orders does not consider price reduction

At the conference call of LI Q1 2024 financial report held today, Li Xiang, chairman of LI, said that the ideal L6 has been widely recognized; Under the brand-new price strategy, the ideals L9, L8 and L7 also showed a continuous good performance. "Overall, we will be very optimistic about the next monthly sales performance. After the adjustment of the price strategy, the orders of L7, L8 and L9 continued to grow, and the company did not intend to reduce prices in the future. "

Tucki’s end-to-end model will get on the bus and will achieve L4-level intelligent driving experience next year.

According to Sina Finance, the end-to-end large-scale model of Tucki was mass-produced, and He Xiaopeng, the chairman of the board, said that automatic assisted driving will gradually change into fully automatic driving. The goal of Xpeng Motors’s end-to-end intelligent driving is to iterate once every two days, improve the intelligent driving ability by 18 times in 18 months, and make every road in the country open in Q3 this year; Realize the L4 intelligent driving experience in 2025.

(): Obtain the supplier’s Xpeng Motors project designation.

Founder Motor announced that it had been informed by customers that the company had become a supplier of parts such as stator and rotor assembly of a certain type of driving motor of Guangzhou Xpeng Motors Technology Co., Ltd.. The project is expected to start mass production and supply in the third quarter of 2025, with a total demand of about 350,000 units within five years of its life cycle.

Li Xiaopeng presided over the seventh collective study of the theoretical study center group of the party group of the Ministry in 2024.

According to the official news of the Ministry of Transport, on May 20th, the theoretical study center group of the Party Group of the Ministry of Transport held the seventh collective study in 2024. Li Xiaopeng stressed that it is necessary to solidly promote the three-year action of tackling the root cause of safety production, further refine the annual work objectives in combination with plans in various fields, timely study and solve key and difficult problems in the work process, strengthen the guarantee of policies and funds, and strictly implement measures such as "civil air defense, technical defense, engineering defense, and management defense" according to time nodes. It is necessary to do a solid job in safety supervision in key areas, do a good job in special governance actions such as joint management of commerce and fisheries, safety of ship collision with bridges, operational safety of urban rail transit, and major disasters on high subgrade and high slope, and carry out in-depth investigation and rectification of safety environment along railways, operational safety of civil aviation, and safety risks of postal delivery. It is necessary to do a solid job in safety production, flood control and typhoon prevention in key time periods and major activities, formulate safety protection plans in advance, promote the supervision and law enforcement forces to sink to the grassroots front line, adhere to the bottom line thinking and extreme thinking, and make good preparations for materials, strength and plans.

Baidu antigen-antibody structure prediction model is far more effective than AlphaFold3.

According to Baidu AI, in the research and development of antibody drugs and polypeptide drugs, the prediction of antigen-antibody and polypeptide protein complex structure plays a vital guiding role, and its accuracy is very important for subsequent research. However, from the current calculation methods, whether it is the energy function tool based on physical method or the method based on deep neural network, including the recently updated AlphaFold 3 of DeepMind, there is still much room for improvement in the structural prediction accuracy of antigen-antibody and protein-polypeptide complexes. In response to this challenge, PaddleHelix team of Baidu propeller developed HelixFold-Multimer model. By optimizing data, network structure and training methods, it has reached the leading position in the industry in predicting the structure of antigen-antibody/polypeptide protein complex. Compared with the existing methods, HelixFold-Multimer is far superior to similar methods, including the newly released AlphaFold 3, in two core key indicators: DockQ and success rate.

LI: Q1 revenue in 2024 was 25.6 billion yuan, compared with 18.79 billion yuan in the same period of last year.

LI Hong Kong Stock Exchange announced that the revenue in the first quarter was 25.6 billion yuan, and the market expected 25.58 billion yuan, compared with 18.79 billion yuan in the same period last year.

LI’s revenue in the first quarter was 25.6 billion yuan, and its performance guidance in the second quarter was lower than market expectations.

LI Hong Kong Stock Exchange announced that the revenue in the first quarter was 25.6 billion yuan, and the market expected 25.58 billion yuan, compared with 18.79 billion yuan in the same period last year. Revenue in the second quarter is expected to be 29.9 billion yuan to 31.4 billion yuan. It is estimated that the delivery volume in the second quarter will be 105,000 to 110,000 vehicles, and the market is estimated to be 130,692 vehicles.

(): The company’s products have not been used in Baidu driverless taxis yet.

On May 20, Yutong Optics said on the interactive platform that the company’s products have not been used in Baidu driverless taxis yet.

Netease Tianyin Ai music tools fully open "Tianyin Magic Gift Shop" activity online cloud village.

Netease Tianyin Platform, a one-stop AI music creation tool under Netease Cloud Music, is open to all users of Netease Cloud Music. It is reported that Netease Tianyin has the auxiliary function of AI creation in the whole process of music creation, such as words, songs, editing, singing and mixing, and has the professional music creation level of productivity. In addition, in order to celebrate the official opening of Netease Tianyin platform, Netease Cloud Music launched a special "magic gift shop" activity. Users can enter the activity page, select the object of giving gifts and get the keywords of gifts, and then go to Tianyin platform to input keywords to generate exclusive songs. (36Kr)

Flying pig: 618 is on sale for 24 hours, and the turnover has exceeded 10 million, and the number of goods has doubled.

At 20:00 on May 18th, the Flying Pig 618 Summer Promotion was officially launched. According to the news of the Flying Pig 618 Project Team, at 24: 00, the activity turnover and the number of bookings continued to grow on the basis of a strong rebound last year, and the number of commodities with turnover exceeding 10 million doubled compared with last year. (36Kr)

At 8 o’clock tonight, 2024 Tmall 618 will be sold in stock.

At 8 o’clock tonight, 2024 Tmall 618 officially kicked off. Taotian Group said that this year Tmall 618 is called "the simplest and most affordable 618 in history", and its main feature is extremely simple, mainly reflected in the cancellation of pre-sale and low price, such as the return of 50% off the venue, the subsidy of 10 billion yuan for the whole family as low as 20%, and the threshold for 88VIP large coupons is lowered. On the basis of low price, the discount will be repeated, among which the beauty coupon is stronger than "double 11", and the highest discount for iPhone15 is 2300 yuan. In terms of the supply of special goods, the reporter was informed that during the period of 618 this year, Tmall will increase the volume of 30,000 bottles of 1499 yuan Maotai, Rolex Rolex and other big-name products to participate in the price subsidy of Tmall 618 for the first time. In addition, in terms of live broadcast, more than 100 stars will appear in Taobao live broadcast room at 618 this year. (Securities Times)

Jingdong Payment and WeChat Payment Realize Interconnection

According to JD.COM, JD.com Payment and WeChat Payment are interconnected, becoming the first third-party payment institution in the industry to get through WeChat personal code and merchant code at the same time. According to market information, there are more than 500 million users in Jingdong, and more than 1 billion users in WeChat.

Baidu responded to Victor Liang, senior vice president, taking over the public relations business: it was previously Jing Jing’s superior

According to media reports, Victor Liang, Baidu’s senior vice president, has temporarily taken over the public relations business after Qu Jing, Baidu’s former vice president of public relations, left his post because of controversial remarks about short videos. It is not clear whether to take over temporarily to find the next public relations director or to take over formally. In this regard, Baidu responded that Victor Liang had been in charge of Baidu’s government relations (GR) and public relations (PR) business before, and the former No.1 public relations officer of Baidu, Qu Jing, had previously reported to Victor Liang. (Sina Technology)

Auto stocks in Hong Kong stocks continued to rise, and Xpeng Motors and Zero Run cars rose by more than 6%.

Auto stocks in Hong Kong stocks continued to rise, with Xpeng Motors and Zero Run cars rising by more than 6%, and LI, Geely Automobile and Guangzhou Automobile Group rising by more than 2%.

Apple Chief Operating Officer Jeff Williams visited TSMC.

Jeff Williams, chief operating officer of Apple, visited TSMC a few days ago, and Wei Zhejia, president of TSMC, personally received it to discuss matters such as Apple’s development of self-developed AI chips and the outsourcing of TSMC’s advanced process capacity to produce related chips. Apple did not respond immediately; TSMC has never commented on market rumors and single customer information. The industry expects that Apple will package the first batch of TSMC’s 2nm production capacity. (science and technology innovation board Daily)

Research: ferrets and cats are susceptible to Covid-19, which can cause "cat-to-cat transmission"

  Covid-19 is thought to originate from bats, and it is 96.2% similar to RaTG13 (collected by Shi Zhengli, Wuhan Institute of Virology, Chinese Academy of Sciences, in Yunnan, China in 2013) in nucleotide sequence level. However, it is a kind of novel coronavirus that has not been detected in humans and other animals before, and its appearance has brought many new problems to be solved urgently, including whether other pets, livestock and poultry may be infected by Covid-19 besides humans?

  On April 8th, local time, the top academic journal Science published the paper "Susceptibility of Ferrets, Cats, Dogs, and Different Domestic Animals to SARS-coronavirus-2" online. The purpose of this study is to find out some questions: Will Covid-19 be transmitted to other animal species, thus becoming a "reservoir" of infection? Covid-19 infection has many clinical manifestations in humans, ranging from mild infection to death, so how is it manifested in other animals? With the development of vaccines and antiviral drugs, which animals can be used to simulate the effects of these drugs or vaccines on humans most accurately?

  In order to solve these problems, research teams from the State Key Laboratory of Veterinary Biotechnology of Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences and the National High-level Biosafety Laboratory of Animal Disease Prevention and Control evaluated the susceptibility of different model experimental animals, pets and livestock to Covid-19, infected Covid-19 through experiments, observed the clinical manifestations and pathological changes of vaccinated animals and cohabiting animals, and detected the viral load of organs and tissues, the emission of respiratory and intestinal viruses, and the seroconversion of antibodies against Covid-19 in animals.

  Their research shows that Covid-19 has weak replication ability in dogs, pigs, chickens and ducks, but it can replicate efficiently in ferrets’ upper respiratory tract and cats’ respiratory system and digestive system. Experimental infected cats can spread Covid-19 through the air; Some cats can cause serious illness or even death after infection, and the illness of young cats is obviously more serious than that of older cats.

  Histopathological observation confirmed that virus infection in cats can cause lung inflammation and intestinal mucosal damage to varying degrees. Immunohistochemical study showed that there were a large number of virus infections in mucosal epithelium and olfactory bulb cells of upper respiratory tract (nasal cavity, maxilla, tonsil), mucous gland epithelial cells of trachea and bronchial mucosa, and intestinal mucosal epithelium.

  The correspondent of this paper is Chen Hualan, academician of China Academy of Sciences, chief scientist of the innovation team of animal influenza basic and prevention research in Harbin Veterinary Research Institute of China Academy of Agricultural Sciences, Bu Zhigao, director of Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences and director of the national high-level biosafety laboratory for animal disease prevention and control, and Wu Guizhen, secretary of the Party Committee of Institute of Viral Disease Prevention and Control of China CDC and director of BSL-3 laboratory. Previously, on March 31st, local time, the research team had taken the lead in publishing the research on the preprint platform bioRxiv.

  It is worth mentioning that the National High-level Biosafety Laboratory for Animal Disease Prevention and Control is one of the existing two P4 laboratories in China, and the other is in Wuhan National Biosafety Laboratory of Chinese Academy of Sciences. All the experiments of Covid-19 infection in this study were carried out in P4 laboratory, which was approved by the Ministry of Agriculture and Rural Affairs of China. Animal research and animal welfare programs were approved by the Animal Experimental Ethics Committee of China Academy of Agricultural Sciences.

  According to the press release issued by official website, Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences, different coronaviruses have been prevalent in mammals and poultry, but most of these coronaviruses are limited to specific species of animals and generally cannot infect humans. Similarly, several common coronaviruses in humans do not infect other animals. However, some coronaviruses from bats, such as SARS and MERS virus, can often infect many animals and humans.

  At present, Covid-19 is popular among a wide range of people in the world, and the risk of introducing animals in close contact with human beings is increasing. Therefore, it is urgent to study the susceptibility of domestic animals in close contact with human beings to Covid-19, evaluate whether domestic animals are exposed to Covid-19 hazards and become potential intermediate hosts, and provide scientific basis for prevention and control of Covid-19.

  In addition, in view of the current global epidemic situation of COVID-19, it is very likely that it will evolve into a common infectious disease, and it is urgent to establish a stable and reliable animal infection model to meet the needs of vaccine and drug research and development evaluation.

  The research team stressed that the monitoring of cat COVID-19 should be regarded as an auxiliary means to eliminate the current Covid-19 epidemic. They called for close monitoring and protection of cats in epidemic areas, avoiding their contact with infectious sources and preventing them from becoming possible transmission hosts or storage hosts.

  In addition, it was previously questioned that cats infected with COVID-19 were caused by large doses under laboratory conditions. However, in addition to this research, on April 3rd, Academician Jin Meilin, professor of the State Key Laboratory of Agricultural Microbiology of Huazhong Agricultural University, director of the Key Laboratory of Veterinary Diagnostic Preparations of the Ministry of Agriculture, director of the Research Center for Emerging Infectious Diseases of Wuhan Institute of Virology, Chinese Academy of Sciences, and researcher Shi Zhengli, director of the Key Laboratory of Highly Pathogenic Biology and Biosafety of Chinese Academy of Sciences, also published a study on the preprint platform bioRxiv. Through the investigation of cat serum, they found that the serum ELISA test of 102 cats collected after the outbreak of COVID-19 in Wuhan showed that the serum from 15 cats (14.7%) was positive for Covid-19 receptor binding domain (RBD).

  Nadia, a 4-year-old tiger from Bronx Zoo in new york, USA, was recently diagnosed with Covid-19. On April 5, local time, the US Department of Agriculture issued a statement confirming that a tiger in a zoo in new york was diagnosed with Covid-19, and several other lions and tigers also showed symptoms of respiratory diseases. Officials at the Bronx Zoo in new york said that nadia, three other tigers and three African lions had symptoms of dry cough and loss of appetite, but they are expected to recover. Public health officials believe that these animals were infected by an asymptomatic employee.

  Covid-19 can be replicated in the upper respiratory tract of ferrets for up to 8 days, but it will not cause serious illness or death.

  Ferrets are often used as animal models of human respiratory viruses. Therefore, the research team first tested ferrets’ sensitivity to Covid-19.

  Two Covid-19 strains were used in this study: F13-E from Wuhan South China Seafood Market and CTan-H from a patient infected with Covid-19.

  The research team inoculated 10 5 PFU (Plaque Forming Unit) F13-E or CTan-H into ferrets through nose respectively, and euthanized them on the 4th day after inoculation (P.I.). The turbinate, soft palate, tonsil, trachea, lung, heart, spleen, kidney, pancreas, small intestine, brain and liver of each ferret were collected, and the viral RNA was determined by qPCR and virus titration.

  Viral RNA:A in ferrets’ organs or tissues: A, F13-E, B, CTAN-H..

  The results showed that viral RNA and infectious virus were detected in the turbinate, soft palate and tonsil of all four ferrets, but not in other tissues.

  C, virus titer in organs or tissues of ferrets inoculated with F13-E, D and CTAN-H.

  The research team believes that these results show that Covid-19 can replicate in the upper respiratory tract of ferrets, but it has not been detected in other tissues.

  In order to study the replication dynamics of virus in ferrets, the research team intranasally inoculated 6 ferrets with 10^5pfu of F13-E(3) or CTan-H(3), and then placed them in three isolated cages. On the 2nd, 4th, 6th, 8th and 10th day, ferret nasal wash and rectal swab were collected for virus RNA detection and virus titration. At the same time, their body temperature and COVID-19 signs were monitored for two weeks.

  Viral RNA in the nasal wash of ferrets inoculated with F13-E(E) and CTan-H(F). Viral titers in the nasal wash of ferrets inoculated with F13-E(G) and CTan-H(H).

  The results showed that viral RNA was found in the nasal wash of all six ferrets on the 2nd, 4th, 6th and 8th day. Viral RNA was also found in some rectal swabs, but the copy number was significantly lower than that of nasal wash. Infectious virus was detected in nasal wash of all ferrets, but none of them was found in rectal swab.

  One ferret in each group developed fever and loss of appetite on the 10th and 12th days respectively. In order to investigate whether these symptoms are caused by virus replication in the lower respiratory tract, the research team euthanized the two ferrets on the 13th day and collected their organs for virus RNA detection.

  However, except for the ferret turbinate inoculated with CTan-H, the low copy number was detected, and no viral RNA was detected in any other tissues or organs.

  Pathological studies showed that two ferrets euthanized on the 13th day had severe lymphoplasmacytic vasculitis and vasculitis, the number of type II alveolar cells, macrophages and neutrophils in alveolar septa and alveolar cavities increased, and the lungs had mild bronchiolitis.

  The asterisk indicates that the animals were euthanized on the 13th day after inoculation, and the other four animals were euthanized on the 20th day.

  Covid-19 antibody was detected in all ferrets by ELISA and neutralization test, and the antibody titers of two ferrets euthanized on the 13th day were significantly lower than those euthanized on the 20th day.

  In order to further study whether Covid-19 was replicated in ferrets’ lungs, the research team inoculated 8 ferrets with 10^5 pfu of CTan-H through trachea, and euthanized 2 animals on the 2nd, 4th, 8th and 14th days, respectively, and detected virus RNA in tissues and organs.

  Among the two ferrets euthanized on the second day and the two ferrets euthanized on the fourth day, the researchers only detected viral RNA; in the turbinate and soft palate of one of them. Among the two ferrets euthanized on the eighth day, viral RNA; was detected in the soft palate of one ferret and in the turbinate, soft palate, tonsil and trachea of the other ferret. No viral RNA was detected in the two ferrets euthanized on the 14th day.

  These results indicate that Covid-19 can replicate in the upper respiratory tract of ferrets for up to 8 days without causing serious illness or death.

  At the end of the paper, the research team also mentioned that, comparatively speaking, Covid-19 is different from other influenza viruses that can replicate in the upper respiratory tract and lower respiratory tract of ferrets, and even human SARS-CoV. Covid-19 is only replicated in ferrets’ nasal bones, soft palate and tonsils. It can also replicate in the digestive tract, but even if the virus is inoculated in the trachea, the virus is still not detected in the lungs of ferrets.

  Cats are highly susceptible to "cat-to-cat transmission": the monitoring of cat Covid-19 should be regarded as an auxiliary means of epidemic prevention and control.

  It is worth noting that cats and dogs are in close contact with humans, so the research team thinks that besides laboratory animals like ferrets, it is very important to know the susceptibility of domestic animals that often live with humans to COVID-19 for the control of Covid-19.

  The research team first studied the replication of Covid-19 in cats. Five 8-month-old subadult domestic cats (inbred lines) were intranasally inoculated with 10^5pfu of CTan-H, and two of them were scheduled to be euthanized on the sixth day to evaluate the virus replication in their organs. Three cats were put in separate cages in the isolator. In order to monitor the spread of respiratory droplets, an uninfected cat was placed in a cage adjacent to each cat vaccinated with the virus.

  Because 8-month-old cats are aggressive, it is difficult to carry out routine nasal cleaning on them. In order to avoid possible harm, the research team collected the feces of these cats and checked the viral RNA in their organs after euthanasia.

  Virus RNA was detected in the nasal bone, soft palate and tonsils of two sub-adult domestic cats euthanized on the 6th day, and virus RNA was also detected in the trachea of one cat and the small intestine of the other cat. However, no viral RNA was detected in any lung samples of these two cats.

  Infectious viruses were detected in the nasal bones, soft palate, tonsils and trachea of these cats, but no infectious viruses were found in the small intestine with positive viral RNA.

  The spread of Covid-19 among cats.

  In the study of virus transmission, RNA virus was detected in the feces of two vaccinated cats on the third day, and RNA virus was detected in the feces of all three vaccinated cats on the fifth day. Among the three cats at risk of virus exposure, viral RNA was detected in the feces of one cat on the third day.

  Virus-infected cats with positive feces were euthanized on the 11th day. Virus RNA was detected in the soft palate and tonsils of the infected cats and in the nasal bones, soft palate, tonsils and trachea of the exposed cats, indicating that respiratory droplets spread between cats.

  On the 12th day, the research team euthanized the remaining cats. Viral RNA was detected in the tonsils of one virus-infected cat and the nasal bone, soft palate, tonsils and trachea of another virus-infected cat, but it was not detected in any organ or tissue of the two virus-exposed cats.

  Through ELISA and neutralization test, Covid-19 antibody was detected in all three cats inoculated with virus and one cat exposed to virus.

  Covid-19 replicates efficiently in respiratory system and digestive system of infected cats, causing pathological damage and inflammatory reaction. Histopathological and immunohistochemical study on cats that died or were euthanized three days after virus infection. (a) The arrangement of nasal mucosa epithelium is disordered, cilia fall off (arrow), and lymphocytes in lamina propria infiltrate (arrow). (b) The tonsil epithelial cells are degenerated and necrotic, and the surface of mucosal epithelium (asterisk) is covered with cell fragments and neutrophils (arrow). (c) Epithelial degeneration and necrosis of tracheal mucosa (arrow), with mucus (asterisk) mixed with a large number of cell fragments on the surface. (d) Epithelial necrosis of tracheal mucous glands and infiltration of lymphocytes (arrow). (e) Normal lung tissue structure of uninfected cats. (f) Aggregation of inflammatory cells in pulmonary blood vessels and coagulation of fibrin (arrow). (g) A large number of macrophages and lymphocytes infiltrated in alveoli, that is, alveolar septa. (h) Infiltration and proliferation of alveoli and alveolar septitis. (i) Some cells in the epithelium of small intestine are degenerated and necrotic, and lymphocytes in the lamina propria are moderately infiltrated (arrow). (j) A large number of epithelial cells of turbinate mucosa were positive for virus antigen (brown). (k) A large number of exfoliated cells in tonsil mucosa epithelium and mucosa surface were positive for virus antigen (brown). (l) A large number of virus antigens were positive (brown) in serous cells of tracheal mucous glands. (m) A large number of small intestinal mucosal epithelial cells were positive for virus antigen (brown). Ruler line A, I = 100 μ m, B-H, J-L = 200 μ m, M = 500 μ m

  The research team also repeated the above-mentioned replication and transmission research in sub-adult cats in young cats (70-100 days). Histopathological studies on the samples of young cats who died or were euthanized on the third day after being inoculated with the virus showed that the nasal cavity and tracheal mucosa epithelium and lungs of the two cats had a lot of damage.

  These results indicate that Covid-19 can be effectively replicated in cats, and young cats are more susceptible to infection. More importantly, the virus can spread from cat to cat through respiratory droplets.

  Next, the research team also studied the replication and spread of Covid-19 in dogs, and the results showed that dogs were less sensitive to Covid-19. Similar studies also show that pigs, chickens and ducks are not sensitive to Covid-19.

  Overall, the research team found that ferrets and cats are highly sensitive to Covid-19, dogs are less sensitive, and domestic animals including pigs, chickens and ducks are not sensitive to the virus.

  In addition, it is reported that Covid-19 uses angiotensin-converting enzyme 2 (ACE2) as its receptor to enter cells, and ACE2 is mainly expressed in type II lung cells and serous epithelial cells of ferrets’ tracheal-bronchial submucosal glands. Therefore, the research team believes that the potential mechanism to prevent Covid-19 from replicating in ferrets’ lower respiratory tract remains to be studied.

  The results of this study show that ferrets can be used as animal models for vaccine and drug evaluation in Covid-19. Dogs, pigs, chickens and ducks are not susceptible to Covid-19, which has important guiding significance for the traceability of virus hosts; More importantly, cats are highly susceptible to Covid-19.

  The research team called for close monitoring and protection of cats in epidemic areas to avoid contact with infectious sources and prevent them from becoming possible transmission hosts or storage hosts. The monitoring of cat COVID-19 should be regarded as an auxiliary means to eliminate the current Covid-19 epidemic.

  Paper link: https://science.sciencemag.org/content/sci/early/2020/04/07/science.abb7015.full.pdf.

Q&A on China’s economy in the two sessions: What do you think of China’s price movement? -The second question and answer of China economy in the two sessions.

    Xinhua News Agency, Beijing, March 6th Question: How do you view China’s price movement? -The second question and answer of China economy in the two sessions.

    Xinhua News Agency reporter Wei Yukun and Wu Yu

    Since last year, China’s price increase has been running at a low level, which has aroused some people’s worries about China’s deflation. How to treat China’s price movement situation? Is China’s economy really in deflation?

    During the two sessions of the National People’s Congress, the reporter interviewed many NPC deputies, Chinese People’s Political Consultative Conference members and authoritative experts to analyze this issue and respond to external concerns.

   Does low prices mean deflation?

    Since October last year, the consumer price index (CPI) has been declining year-on-year, and it will drop by 0.8% in January 2024. At the same time, the national producer price index (PPI) continued to decline.

    The low price has caused some worries about whether China’s economy will fall into deflation.

    To judge whether we are caught in deflation, we must first clarify the concept. Generally speaking, in economics, deflation mainly refers to the continuous negative growth of prices and the downward trend of money supply, which is usually accompanied by economic recession. This depends not only on the "shape" of price operation, but also on the "state" of money supply and the "potential" of economic development.

    -Price operation: generally low, maintaining a moderate upward trend.

    According to the government work report submitted for deliberation on the 5th, the consumer price of China residents rose by 0.2% in 2023. This data is in stark contrast to the high inflation in major developed economies.

    Jin Li, member of Chinese People’s Political Consultative Conference and vice president of south university of science and technology of china, said that last year, the core CPI excluding volatile food and energy prices rose by 0.7% year-on-year, indicating that the supply and demand of industrial consumer goods and service consumption in China were generally stable. The year-on-year decline of PPI also decreased by 5.4% from the highest in June last year to 2.5% in January 2024.

    Since last year, China’s monthly price level has always fluctuated moderately within a reasonable range. In January 2024, CPI rose by 0.3% month-on-month, which has been rising for two consecutive months.

    -Money supply: the total amount is moderate and the rhythm is stable.

    By the end of January 2024, the balance of broad money (M2) in China was 297.63 trillion yuan, up 8.7% year-on-year. Under the background of high base in the same period last year, it maintained a reasonable growth rate.

    The scale of social financing is a comprehensive indicator of financial support for the real economy. In January, the scale of social financing in China increased by 6.5 trillion yuan, 506.1 billion yuan more than the same period of last year.

    -economic development: the overall recovery is improving.

    In 2023, China’s economy generally rebounded, with a GDP growth rate of 5.2%, which was faster than the average growth rate of 4.5% in the three years of the epidemic, and also significantly faster than the economic growth rates of 2.5% in the United States, 0.5% in the euro zone and 1.9% in Japan, making it an important engine of global economic growth.

    Since 2024, China’s manufacturing purchasing managers index, SME development index and other indicators have rebounded from last December. The International Monetary Fund (IMF) recently raised its forecast for China’s economic growth this year and cast a "vote of confidence" for China’s economy.

    "Deflation is often the result of long-term accumulation of structural problems in economic operation. Judging deflation should not only focus on one or two price indicators." Huang Maoxing, deputy to the National People’s Congress and vice president of Fujian Academy of Social Sciences, said that on the whole, there is no deflation in China, let alone deflation spillover, and the so-called "economic deflation in China" is totally a false proposition.

    Not long ago, ING reported that the discussion about deflation in China was exaggerated by the outside world. In January, the overall CPI and core CPI in China both rose month-on-month, reflecting that China has not fallen into a "deflation spiral".

    "We don’t expect an overall deflationary trend in China." Gita Gopinath, First Vice President of IMF, said not long ago.

   What are the reasons for the low price increase?

    Prices are related to economic operation and affect people’s lives. At present, the low price increase in China is the result of multiple factors.

    "After the smooth transition of epidemic prevention and control, domestic production has accelerated recovery, logistics has remained smooth, and product supply is sufficient. However, demand is constrained by factors such as expected instability and income distribution differentiation, and recovery will take some time." Xu Guangjian, vice president of China Price Association, said that the time difference between supply and demand recovery is the main factor for the lower prices.

    Commissioner Jin Li said that in 2022, due to the Ukrainian crisis, food and energy prices were higher, which made the CPI increase in 2023 relatively low. In addition, the price of pork occupies a high weight in China CPI. Due to the abundant supply of live pigs and pork and the sluggish consumption of superimposed pork, the domestic pig price continues to fall, which lowers the CPI increase.

    Input factors also have an impact on China’s prices. After the epidemic, in order to cope with high inflation, major central banks in the United States and Europe quickly and intensively adjusted their monetary policies, and the year-on-year increase of CPI in the United States and Europe has dropped from the previous high of about 10% to the current 3%. "The inflation level in developed economies has fallen faster than expected, which has an impact on the price level in China." Pan Gongsheng, governor of the People’s Bank of China, said.

    Xing Ziqiang, chief economist of Morgan Stanley in China, said that China’s lower prices may have a positive spillover effect on global trade goods prices, which will help alleviate the "sequela" of unconventional stimulus policies adopted by some economies in response to high inflation.

    The experts interviewed agreed that the factors that caused the current low price operation in China are mainly phased, cyclical and seasonal, not trending, and its influence should not be exaggerated.

    This year’s government work report sets the expected target of annual consumer price increase at around 3%. According to the plan report submitted for review on the 5th, the main consideration for setting this goal is to comprehensively analyze the hikes of price changes in 2023 and the new price increase factors in 2024. It is expected that consumer prices will rise moderately in 2024.

    "This expected goal is consistent with last year’s expected goal, in line with the overall trend of domestic price stabilization and recovery, and leaves some room for strengthening macro-policy regulation and deepening price reform." Yu Miaojie, deputy to the National People’s Congress and president of Liaoning University, said.

   How to prevent the risk of deflation?

    Delegates and experts interviewed said that although the low domestic price operation is temporary, we should be alert to and guard against deflation risks, and actively and effectively solve problems such as insufficient effective domestic demand and overcapacity in some industries.

    -Strengthening macro-policy control.

    The government work report pointed out that the liquidity should be kept reasonable and sufficient, and the scale of social financing and money supply should match the expected goals of economic growth and price level.

    "Maintaining a reasonable and sufficient liquidity is an effective measure to prevent deflation risks. This year’s government work has clearly promoted the steady decline of comprehensive social financing costs, which is expected to further stimulate the effective demand of the real economy and enhance residents’ willingness to consume and invest. " Ceng Gang, director of Shanghai Finance and Development Laboratory, said.

    A proactive fiscal policy should moderately increase efforts, improve quality and increase efficiency; A prudent monetary policy should be flexible, moderate, accurate and effective; Incorporate non-economic policies into the consistency assessment of macro-policy orientation … A number of arrangements in this year’s government work report have strengthened policy co-ordination to ensure that efforts are made in the same direction and joint efforts are formed.

    -Promote the formation of a virtuous circle in which consumption and investment promote each other.

    Han Baojiang, a member of Chinese People’s Political Consultative Conference and a professor at the Central Party School (National School of Administration), said that at present, the key to preventing deflation risks is to expand domestic demand, release the potential vitality of the super-large-scale market, and enhance the ability and confidence to resist external imported risks.

    When deploying this year’s tasks, the government work report pointed out that the implementation of the strategy of expanding domestic demand should be organically combined with deepening the structural reform on the supply side, so as to better coordinate consumption and investment and enhance the pulling effect on economic growth.

    Optimize the consumption environment, carry out the "consumption promotion year" activity and implement the "rest assured consumption action"; Deepen the cultivation and construction of international consumption center cities; Promote the construction of additional national debt projects with high quality; We will implement a new cooperation mechanism between the government and social capital, and encourage private capital to participate in major project construction … The government work report and the plan report will focus on expanding domestic demand this year.

    "With the implementation of a series of policies to expand domestic demand, giving full play to the key role of investment in optimizing the supply structure and promoting the upgrading of domestic consumption structure, the domestic economic cycle will be further smooth." Qu Yongyi, member of Chinese People’s Political Consultative Conference and secretary of the Party Committee of the Institute of Industrial Economics of the Chinese Academy of Social Sciences, said.

    Ayhan Gauss, deputy chief economist and director of the forecasting bureau of the World Bank, said that a series of policies adopted by China at present are very correct, which can boost consumer confidence and consumption in the short term, and enhance the long-term economic growth potential through firm reforms.

OPPO machine emperor is here! Find X7 series core tricks inventory

This week, OPPO announced the latest technological progress in AI, performance, communication and privacy security, including the first handset/hands-free dual-mode satellite call for smart phones, the first 7 billion-parameter large model for end-side applications, the tidal architecture that debuted and many other cutting-edge technologies.

The brand-new technology portfolio announced this time will fully implement the next-generation flagship product Find X7 series, set a brand-new technical benchmark for the flagship mobile phone in 2024, and bring consumers an innovative flagship experience that refreshes standards.

Release handset/hands-free dual-mode satellite call, leading the evolution of satellite interphone to satellite mobile phone.

OPPO released the satellite antenna pattern control technology, which will realize the innovative experience of handset/hands-free dual-mode satellite call for the next generation flagship. This technology can dynamically adjust the radiation pattern of satellite antenna, make the antenna beam aim at the satellite dynamically, and ensure that users can keep connected and talk with the satellite in both handset and hands-free conversation postures.

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Lu Bao, a terminal antenna expert in OPPO hardware engineering, said: "We are very happy to realize the latest breakthrough in satellite antenna technology in the next generation flagship product for the first time through continuous research and accumulation and using a series of innovative technologies and patents. Through satellite communication technology and fully upgraded antenna, smart communication and near-field communication technology, we expect users to get a reliable communication experience in the whole scene. "

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The traditional satellite communication mobile phone adopts single antenna design, and it can’t meet the demand of transmitting power in the head-to-hand state. It can only support the use of hands-free mode, which will lead to problems such as unclear communication in harsh weather environment such as strong wind.

OPPO’s brand-new handset/handsfree dual-mode satellite call makes the mobile phone satellite call experience evolve from "satellite intercom mode" to "satellite phone mode" which accords with users’ intuition for the first time, helping users to obtain more efficient communication efficiency in extreme environments.

The industry’s first end-to-end application of the 7 billion parameter big model, the big model mobile phone entered the fast lane.

Facing the rapid development of large-scale model technology, OPPO officially launched the large-scale model of self-training in ODC — — After AndesGPT, it was also announced that the industry’s first 7 billion-parameter model of end-side application will be realized on Find X7 series.

Through the model compression such as high-precision 4-4bit quantization, the acceleration of reasoning engine and the hardware acceleration mode of deep cooperation with chip platform,For the first time, it brings a complete 7 billion-parameter large model to the mobile phone terminal, completely changing the way of using the mobile phone terminal AI.

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Zhang Jun, general manager of OPPO Software Innovation Center, said: "OPPO’s self-trained and personalized big model — — AndesGPT contains many versions of parameters from one billion to one hundred billion, with abundant knowledge, infinite memory and good use of tools. The technical architecture of end-cloud collaboration can support diversified application scenarios.

With the cooperation of various technologies, we will also apply a large language model with 7 billion parameters and a generative visual model to the Find X7 series for the first time, which will bring a local AI experience with faster response, stronger processing ability and higher generation quality while ensuring the privacy and safety of users. "

OPPO machine emperor is here! Find X7 series core tricks inventory

Thanks to the complete ANDES GPT 7 billion-parameter large language model applied by end-side, Find X7 series will bring the next generation AI experience such as natural language understanding, text content summary and call voice summary.

Compared with other models on the same platform, oppoandesgpt 7 billion parameter large language model can bring 20 times faster response in the generation of 200-word prefix, and 2.5 times faster for the generation of 2000-word prefix.

OPPO machine emperor is here! Find X7 series core tricks inventory

At the same time, OPPO’s AndesGPT can achieve the maximum number of abstract words of 14,000, which is 3.5 times that of other models on the same platform. In terms of generation quality, compared with the 1 billion parameter model, the ANDES GPT 7 billion parameter large language model has a higher "IQ" understanding ability, which brings a more complete and accurate record to the call summarization ability.

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OPPO also announced the AndesGPT generative visual model based on self-training, which will bring image semantic understanding, subject recognition and segmentation, image extension and generation capabilities to Find X7 series, and bring a new functional experience of subject elimination and real-life redrawing. AndesGPT’s generative visual mode brings a wider range of image experience to mobile phones.

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Compared with other cloud models on the same platform, AndesGPT can only support human body recognition. ANDES GPT not only supports the recognition and segmentation of more than 120 kinds of subjects, but also can realize hair-level segmentation and multi-agent separation of up to six, as well as the filling and natural generation of super-large-area images, which greatly expands the application scope and practicability of the generative visual model.

In addition, the end-to-end application of AndesGPT generative visual model also brings 60% shorter generation time and higher generation accuracy compared with other models on the same platform, bringing users a more readily available generative visual experience.

OPPO machine emperor is here! Find X7 series core tricks inventory

Original tidal architecture, breaking through the bottleneck of chip energy efficiency

Facing the more stringent demand of flagship end users for chip energy efficiency, OPPO first announced the exclusive tidal architecture technology. As a technology stack of chip hardware and software integration, Tide Architecture has built a set of chip-level performance solutions from scene recognition, computing power demand, cache matching and computing power scheduling, which solves the problems of memory and computing separation and chip scheduling faced by mobile platforms and realizes the maximum energy efficiency performance of flagship chips.

OPPO machine emperor is here! Find X7 series core tricks inventory

Hong Hansheng, director of software technology planning and architecture design of OPPO, said: "Tidal architecture is a collection of chip soft and hard fusion technologies developed by OPPO, and it is a chip optimization technology created by a group of people who know chips.

In the past, from the first-level cache to the system cache has always been the technical area of chip design companies. Through the tidal architecture OPPO, it broke through the technical boundary and mastered the use of the third-level cache to the system cache. With the chip-level capabilities in no man’s land and deep water, it brought a great leap in computing efficiency to the flagship products. "

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Through in-depth joint research and development with chip manufacturers, OPPO has penetrated the tidal architecture into the on-chip cache system that traditional mobile phone manufacturers can’t use finely, and jointly designed cache partition, dynamic ratio of CPU/GPU and fast channel scheme of clean data with chip manufacturers.

Through the tidal architecture, OPPO realizes the dynamic matching of system-level cache for the first time.Dynamically allocate system-level cache resources for CPU and GPU in real time according to computational tasks and rendering tasks. Through this unique technology, the tidal architecture can achieve an average energy efficiency gain of 8%.

OPPO machine emperor is here! Find X7 series core tricks inventory

In addition, the tidal architecture also supports a brand-new scene-level computing power and power consumption analysis model on the chip, which can realize the dynamic computing power and power consumption evaluation and analysis based on a single scene, and dynamically disassemble each computing task to the computing power distribution of each computing unit on the chip in real time, find out the best energy efficiency combination, and achieve more competitive energy efficiency performance for diverse user applications.

By accurately and dynamically scheduling the computing power of GPU, Tide Architecture can also control the display delay excellently, and realize an unprecedented continuous and smooth experience for Android flagship. In the test of simulating users to start applications 320 times a day, the standard deviation of Find X7 equipped with tidal architecture is only 11ms, which has achieved a more lasting and stable smooth performance than the same platform and other platforms.

Hong Hansheng also revealed that OPPO has begun to deeply participate in the design of the next generation of Tianqi chips and explore more possibilities of tidal architecture.

Super signal engineering, solving network problems in the whole scene

During the communication meeting, OPPO also announced a set of self-developed communication technology solutions — — Super signal engineering, through antenna technology, intelligent communication and near-field communication, enhances the full-scene communication experience of Find X7 series from outdoor to urban and from urban to indoor.

OPPO machine emperor is here! Find X7 series core tricks inventory

OPPO brings the highest performance four-antenna architecture to the next generation flagship product through antenna miniaturization technology and spatial distribution optimization of low-frequency four-antennas. By combining low ECC and high isolation technology, OPPO can further improve the throughput of ultra-low frequency four antennas and reduce network delay.

Facing the influence of the grip on the signal strength, OPPO specially designed the low-frequency antenna, built the signal model of OPPO’s self-developed handheld state, improved the signal condition of the mobile phone in the handheld state, and realized the signal strength enhancement of up to 7dB and an average of 3dB.

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OPPO’s unique intelligent communication technology utilizes the intelligent computing service provided by Andean intelligent cloud, the industry-leading intelligent fusion link technology and the cross-layer data acceleration capability to realize the acceleration strategy of the combination of Wi-Fi and cellular multi-networks.

In addition, based on communication QoS link technology, OPPO accelerates conference data and improves conference delay through the establishment of 5G boutique private networks of three major operators.

Smart communication technology also brings AI network prediction technology to Find X7 series. By integrating AI technology, communication technology and sensing technology, Find X7 series can predict signals for different spatial forms, intelligently recommend the most appropriate internet use strategy, and provide better performance in scenarios such as short video jam of subway and optimal network probability of switching from home to home.

Through intelligent communication technology, Find X7 series will also support excellent cross-end unified communication. Through Pantanal trust chain technology, Find X7 can realize fast and non-inductive connection between mobile phone and tablet, and based on the self-developed virtual data transmission channel, the tablet has mobile phone network communication capability, and users can make calls, send and receive short messages and access the Internet with data.

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Super Signal Engineering will also bring a brand-new near-field communication experience to Find X7. Using the through-the-wall mode of near-field communication, Find X7 dynamically selects the optimal transmission and reception time slots through active noise identification, and improves the anti-interference ability. Combined with radio frequency enhancement technology, Find X7 improves the uplink and downlink rates.

Through the high throughput mode, Find X7 series can use the brand-new bandwidth of 160Mhz for mobile phone moving transmission, and can complete the handling of 180GB content in less than 15 minutes.

Using the dual-antenna packet loss prevention technology, Find X7 series can also bring lower Wi-Fi network delay. Using Wi-Fi& Bluetooth full acceleration 3.0 technology, Find X7 series can solve the data transmission impact of Wi-Fi and Bluetooth in traditional solutions. Compared with other products, this technology helps Find X7 series to reduce the game delay of nearly 150ms and 18 live broadcasts.

Protect security and privacy from software to hardware.

While promoting innovation in AI, performance and communication technology, OPPO always attaches great importance to users’ privacy security, and is committed to building a comprehensive privacy protection system for users through full-link application, data management and control, and innovative functions combining software and hardware.

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In order to further enhance users’ privacy protection, OPPO has brought a security solution based on the second-level security chip with the highest security level in the mobile phone industry, which will provide the terminal with the highest chip-level privacy protection.

Compared with the traditional software security scheme, the chip-level encryption method can separate the management and authorization switch of sensitive rights from the operating system and lock it into the hardware layer of the security chip, which is managed by the chip-level security subsystem.

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Based on the chip-level privacy security scheme, OPPO has implemented an innovative VIP mode in the folding flagship FindN3. With OPPO’s unique three-stage physical switch, it can quickly and intuitively turn off sensitive permissions such as microphone, camera and positioning, and encrypt user privacy information at hardware level.

OPPO machine emperor is here! Find X7 series core tricks inventory